Principles in Neuroscience
Neuroendocrinology and Behaviour
Neurogenetics
Neurotoxicology
Nervous system assembly is orchestrated by a balance between progressive and regressive events. Progressive events include neuron generation and survival, synapse formation, axon growth etc. while the regressive events comprise neuron death, synapse restriction and axon degeneration. Abnormal neuron death is reported in several neurodevelopmental disorders and neurodegenerative diseases like Down’s syndrome, Familial dysautonomia, Amyotrophic Lateral Sclerosis (ALS), Parkinson’s and Alzheimer’s disease.
Our research group is interested in understanding the cellular and molecular mechanism of neuron death during normal nervous system development, neurodevelopmental disorders and neurodegenerative diseases. Specifically, how the death signals are transported from one end of the neuron to their cell body. To investigate the mechanism of death signal transport, we work with primary neurons cultured in microfluidic devices and rodents in vivo. In addition to classical cell and molecular biology tools, we also analyse the neurons by advanced microscopy in vitro in microfluidic devices as shown below.
In addition to teaching the courses mentioned for me the program structure of the respective undergraduate or post graduate programmes, I also do journal club style classes with students to buildup scientific temperament and increase awareness about the upcoming cutting-edge neuroscience research. For our journal clubs we also discuss primary literature that depict impactful pioneering discoveries, innovative concepts and technology development.
Amity Institute of Neuropsychology and Neurosciences (AINN)
J1 Block, Room No. 222A