Dr. Ujjaini Dasgupta

Professor

Amity Institute of Integrative Sciences & Health (Manesar)

Molecular Biology, Biochemistry, Cell Biology
Amity Institute Of Integrative Sciences And Health

Amity University Haryana, Amity Education Valley, Pachgaon, Manesar, Gurgaon, Haryana 122413

Phd- Plant Molecular Biology; Department Of Plant Molecular Biology, University Of Delhi South Campus, 2004
Msc- Biophysics, Molecular Biology & Genetics, Department Of Biophysics, Molecular Biology & Genetics University Of Kolkata, 1996
Bsc- Botany, Botany, Chemistry, Zoology; Presidency College, University Of Kolkata; 1994
20 Years
Cell Biology & Genetics BTE 2301- Bsc Bt
Cell Biology & Genetics Lab BTE 2307- Bsc Bt
Cell & Molecular Biology Lab BTH 4111- Msc Bt
Genetic Engineering & Molecular Biology BTH 4215- Msc Bt
Molecular Biology-Phd Coursework
Dr Ujjaini Dasgupta Attempts To Decode The Intricacies Of Sphingolipid Signalling In Tumor Progression Using Multidisciplinary Approaches Including Lipidomics, Transcriptomics, Molecular Biology, And Bioinformatics. She And Her Group Are Interested In Studying Epigenetic, Transcriptional And Post-Transcriptional Mechanisms Regulating Diverse Signalling Pathways During Tumor Development, And Those Targeting The Tumor Microenvironment In Response To Cancer Chemotherapeutics (Acs Central Sci, 2019; Nanoscale, 2020, 2021; Angew. Chem. Int. Ed. 2021, Sci. Adv. 2023). In Collaboration With Clinicians We Also Work With Patient Samples With The Objective To Identify Sphingolipid-Based Prognostic And Diagnostic Biomarkers That Can Have Therapeutic Potential As Well (Cell Death Dis. 2021; Int. J. Cancer. 2023).
Molecular Biology, Cell Biology, Omics As Tools For Diagnosis & Prognosis
Completed Projects: 1) Identification Of Sphingolipid-Based Biomarkers For Triple Negative Breast Cancer Cell And Tissue Types For Identification Of Potential Metastatic Biomarkers; Serb Ecra; 21/03/17-30/09/20 2) Unravelling The Role Of Mtorc2 In Regulation Of Sphingolipid Biosynthesis In Mammalian Breast Cancer Cells; Dbt Biocare; 24/03/2017- 23/09/20 3) Combating Topical And Medical Device Related Multidrug Related Fungal Infections Using Molecularly Engineered Anti-Fungal Hydrogel: Dbt; 07/03/19- 06/03/2023 4) Identification Of Sphingolipid-Based Biomarkers For Triple Negative Breast Cancer(Tnbc) And Luminal A Patients And Their Clinicopathological Correlation; Icmr; 15/03/21- 14/03/24 Ongoing Projects: 1) Elucidating The Role Of Post-Transcriptional Role Of Sphingolipid Metabolic Genes In Breast Cancer Progression- Serb/Crg; 30/12/21- 29/12/24 2) Elucidation Of The Role Of Udp-Glucose Ceramide Glucosyltransferase (Ugcg) In Mtorc2-Mediate Regulation Of Sphingolipid Biosynthesis; Dbt; 22/09/23-21/09/26 3) Elucidating The Role Of Lipid Deregulations In Immunogenic Cell Death In Response To Chemotherapy; Dbt; Approved 4) Identification Of Sphingolipid And Eicosanoid-Based Signatures As Potential Diagnostic, Prognostic And Therapeutic Targets For Inflammatory Bowel Disease Subtypes; Icmr; Approved
Member Of Society Of Biological Chemists, India (Sbci)
Member Of Indian Society Of Translational Research (Istr)
Member Indian Association Of Cancer Research (Iacr)
Member Indian Cancer Genome Atlas (Icga)
Co-Ordinator And Faculty-In-Charge Of Amity Lipid Research Facility (Alrf), Auh
Member Secretary Institutional Ethics Committee
Member Institutional Biosafety Committee
Member Cirf Committee
Departmental Co-Ordinator, Funded Projects
Women Scientist Award- DBT BioCaRE(2017)
Early Career Research Award (2017)
Senior Research Fellowship from Council of Scientific and Industrial Research (CSIR), Govt. of India

Grants:

1. Unravelling the Role of mTORC2 in Regulation of Sphingolipid Biosynthesis in Mammalian Breast Cancer Cells; funded by Department of Biotechnology.
DBT, BioCaRE (2017-2020).

2. Comparative Sphingolipid Profiling of Breast Cancer Cell and Tissue Types for Identification of Potential Metastatic Biomarkers; funded by Department of Science and Technology.
SERB, ECR (2017-2020)

3. Combating topical and medical device related multidrug related fungal infections using molecularly engineered anti-fungal hydrogel.
DBT, EMR (2018-2021)
Amity Institute Of Integrative Sciences And Health
Amity University Haryana, Amity Education Valley, Pachgaon, Manesar, Gurgaon, Haryana 122413