Prof. (Dr.) Maryam Sarwat

Professor

Amity Institute of Pharmacy

Pharmaceutical Technology
PHARMACY

Amity University Noida UP

M.Sc., Ph.D, Postdoc
23 years of Research and Academics
Teaching B.Pharm and PhD students
Herbal Drug Discovery, Potential herbal compounds for combatting human diseases (Cancer, neurodegeneration, bone regeneration, wound healing etc.), Molecular Signalling network study through in silico, in vitro and animal approaches.
Pharmaceutical Biotechnology, Molecular Biology, Molecular Pharmacology, Microbiology
Membership of International Scientific Communities
• Member of the ‘Society of Experimental Biology (SEB)’, London.
• Life Member of Asian Polymer Association.
• Life Member of National Environment Science Academy, India
• Life Member of Society of Pharmaceutical Education and Research (SPER).
Research Projects Completed:
1)DBT project on Stress Signalling by an ER chaperone Calnexin (Total grant Rs. 13 Lakhs For 3 years)
2)DST project on Crosstalks in ER-Stress and Abiotic Stress (Total grant Rs. 25 Lakhs For 3 years)
3)CCRUM project on DuK (Total grant 37 Lakhs for 3 years)
4)SERB project on Yeast two hybrid Assay and FRET (Total grant 33 Lakhs for 3 years)

Research Projects Ongoing:
1) CCRUM project on Antiviral Activity of Herabl drugs (Total grant Rs. 23 Lakhs For 3 years)
2) CCRUM project on Neuroprotective activity of Herbal Drugs (Total grant 31 Lakhs for 3 years)
3) DHR project on Bone Regeneration (Total grant 51 lakhs for 3 years)

Selected Publications in Journals:
1. Sharma N, Gupta M, Anand P, Akhter Y, Al-Dayan N, Majed HA, Biswas S, Ali S, Maryam Sarwat (2023) Kaempferol induces autophagy and apoptosis in liver cancer cells through ER-stress signaling pathway: an in silico and in vitro study. Oncotarget. Impact Factor 5.1. (in press)
2. Sharma N, Gupta M, Nabi G, Biswas S, Ali S, Maryam Sarwat (2023) Variation in the anticancer, antioxidant and antiobesity potential of different polarity extracts of saffron petals. 3 Biotech. Springer. Impact Factor 2.9. (in press) 10.1007/s13205-023-03669-x.
3. M Gupta, D Singh, S Rastogi, HR Siddique, N Al-Dayan, A Ahmad, Sikander M, Maryam Sarwat (2023) Anti-cancer activity of guggulsterone by modulating apoptotic markers: a systematic review and meta-analysis. Frontiers in Pharmacology 14: 1155163. doi: 10.3389/fphar.2023.1155163. Impact Factor 5.9
4. Afsar Raza Naqvi, Samia Haseeb Khan, Deepti Mittal, Huda Alshaya, Mohsin Kazie, Maryam Sarwat (2023) Time-dependent oscillation of pre-MiRNAs, mature MiRNAs and MiRNA targets in tomato plants subjected to varying abiotic stress conditions. Saudi Journal of Biological Sciences: 103157 (in press). https://doi.org/10.1016/j.sjbs.2022.01.029. Impact Factor 4.2
5. Meenakshi Gupta, S Sumaiya, S Ali, T Naved, A Sharma, A Ahmad, M Sikander, Maryam Sarwat (2023) Pharmacognostical and Phytochemical Evaluation of a Unani polyherbal formulation Dawa ul Kurkum. Separations 10 (2), 89. Impact Factor 3.3
Year 2022

6. Meenakshi Gupta, Maryam Sarwat (2022) Nutraceutical interventions for anaemia. Annals of Phytomedine. 11(2): 75-81, 2022, DOI: 10.54085/ap.2022.11.2.8.
7. Nidhi Sharma and Maryam Sarwat (2022) Functional foods for better health and weight loss. Annals of Phytomedine. 11(2): 114-121, DOI: 10.54085/ap.2022.11.2.12.
8. Meenakshi Gupta, Shaikh Maryam Ghufran, Tasneem Kausar, Rafat Ali, Subhrajit Biswas, Shahid M Nayeem, Romana Ishrat, Sher Ali, Ajaz Ahmad, Irfan A. Rather, Maryam Sarwat (2022). z-Guggulsterone is a potential lead molecule of Dawa-ul-Kurkum against hepatocellular carcinoma. Molecules. Impact Factor 4.9. 27(16): 5104. doi: 10.3390/molecules27165104.
9. Meenakshi Gupta, Kumari Chandan, Maryam Sarwat (2022) Natural products and their derivatives as Immune Check Point Inhibitors: Targeting cytokine/chemokine signalling in Cancer. Seminars in Cancer Biology. Impact Factor 17. S1044-579X (22) 00153-5. doi: 10.1016/j.semcancer.2022.06.009.
10. Agarwal, Aakanksha; Kumar, Arun; Garg, Piyush; Chakraborty, Arnab; Verma, Ranjan; Sarwat, Maryam ; Gupta, Ajay; Sasmal, Pijus; Verma, Yogesh; Chowdhury, Chiranjit; Mukherjee, Monalisa (2022) Algal biomass loaded hydrogel scaffolds as a biomimetic platform with antibacterial and wound healing activity. ACS Applied Polymer Materials. Impact Factor 5. 4, 8, 5800–5812
11. Deepti Singh, Meenakshi Gupta, Maryam Sarwat, Hifzur R. Siddique (2022) Apigenin in cancer prevention and therapy: a systematic review and meta-analysis of animal models. Critical Reviews in Oncology / Hematology 176: 103751. Impact Factor 6.3.
12. Rastogi S, Kalaiselvan V, Bin Jardan YA, Zameer S, Maryam Sarwat (2022) Comparative Study of Adverse Drug Reactions Associated with Filgrastim and Pegfilgrastim Using the EudraVigilance Database. Biology 2022, 11: 340. https://doi.org/10.3390/biology11020340 Impact Factor 5.03.
13. Meenakshi Gupta, Jamal Akhtar, Maryam Sarwat (2022) MicroRNAs: regulators of immunological reactions in hepatocellular carcinoma. Seminars in Cell and Developmental Biology 124: 127-133. ISSN: 1084-9521. Impact factor 7.49.
14. Naqvi AR, Maryam Sarwat (2022) MicroRNAs and Immunity. Semin Cell Dev Biol. 124:1-2. Impact factor 7.49 (EDITORIAL)
15. Patel S, Chopra S, Chaurasia S, Sarwat M (2022) Plant based bioavailability enhancers. Current Pharmaceutical Design. 28(8):642-654 doi: 10.2174/1381612828666220112141355) Impact Factor 3.2.
Year 2021

16. Harsha Negi, Meenakshi Gupta, Ramanpreet Walia, Moayad Khataibeh, Maryam Sarwat (2021) Medicinal plants and natural products, more effective and safer pharmacological treatment for the management of obesity. Curr Drug Metab. 22: 918-930. ISSN: 1875-5453 (Online), ISSN: 1389-2002 (Print) Impact factor 3.4.
17. Nidhi Sharma, Subhrajit Biswas, N Al-Dayan, AS Alhegaili, Maryam Sarwat (2021) Antioxidant role of kaempferol in prevention of hepatocellular carcinoma. Antioxidants 10: 1419. Impact factor 7.6.
18. Dhondup Namgyal, K Chandan, S Ali, A Ahmad, MJ Hashim, Maryam Sarwat (2021) Aberrant lighting causes anxiety-like behavior in mice but curcumin ameliorates the symptoms. Animals 11: 2590. Impact Factor 3.2
19. Shruti Rastogi, Vivekananda Kalaiselvan, Sher Ali, Ajaz Ahmad, Sameer Ahmad Guru, Maryam Sarwat (2021) Efficacy and safety of filgrastim and its biosimilars to prevent febrile neutropenia in cancer patients: a prospective study and meta-analysis. Biology, 10, 1069. https://doi.org/10.3390/biology10101069. Impact Factor 5.03.
20. Dhondup Namgyal, Sher Ali, Muhammad Delwar Hussain, Mohsin Kazi, Ajaz Ahmad, Maryam Sarwat (2021) Curcumin ameliorates the Cd-induced anxiety-like behavior in mice by regulating oxidative stress and neuro-inflammatory proteins in the prefrontal cortex region of the brain. Antioxidants 10, 1710. https://doi.org/10.3390/antiox10111710. Impact factor 7.6.
Year 2020

21. Namgyal D, Chandan K, Sultan A, Aftab M, Ali S, Mehta R, Sarwat M (2020) Dim light at night induced neurodegeneration and ameliorative effect of curcumin. Cells 9(9), 2093; https://doi.org/10.3390/cells9092093. Impact factor 7.6
22. Namgyal D, Ali S, Mehta R, Sarwat M (2020) The Neuroprotective effect of curcumin against Cd-induced neurotoxicity and hippocampal neurogenesis promotion through CREB-BDNF signaling pathway. Toxicology 442: 15242. Elsevier. doi:10.1016/j.tox.2020.152542. Impact Factor 4.2. ISSN: 0300-483X. 15 citations
23. Namgyal D, Chandan K, Ali S, Mehta R, Sarwat M (2020) Curcumin improves the behaviour and memory in mice by modulating the core circadian genes and their associated micro-RNAs. Journal of Pharmacology and Pharmacotherapeutics 11: 44-52. ISSN: Print -0976-500X, Online - 0976-5018
24. Srishthi Aggarwal, Chandni Sardana, Munir Ozturk, Maryam Sarwat (2020) Plant stem cells and their applications: special emphasis on their marketed products. 3 Biotech 10: 291 https://doi.org/10.1007/s13205-020-02247-9. Impact Factor 2.46, Springer. ISSN: 2190-572X
25. Sarwat M, Ozturk M (2020) Molecular signaling during communicable and non-communicable diseases. Current Pharmaceutical Design. 26: 395. doi: 10.2174/138161282604200306111452. Impact Factor 3.1 (EDITORIAL)
26. Chandan K, Gupta M, Sarwat M (2020) Role of host and pathogen-derived MicroRNAs in immune regulation during infectious and inflammatory diseases. Frontiers in Immunology. 10:3081. Impact Factor 7.56. doi: 10.3389/fimmu.2019.03081. 42 citations.
27. Gupta M, Chandan K, Sarwat M (2020) Role of miRNA and long non-coding RNA in hepatocellular carcinoma. Current Pharmaceutical Design. Impact Factor 3.1. 26: 415-428. 14 citations.
28. Rastogi S, Shukla S, Sharma AK, Sarwat M, Srivastava P, Katiyar T, Kalaiselvana V, Singh GN (2020) Towards a comprehensive safety understanding of granulocyte-colony stimulating factor biosimilars in treating chemotherapy associated febrile neutropenia: Trends from decades of data. Toxicology and Applied Pharmacology 395: 114976. Impact Factor 4.46. ISSN: 0041-008X
29. Mirza K, Archana Sharma, Tanveer Naved, Jamal Akhtar, Maryam Sarwat (2020) New technologies and interventions for the standardization of Unani drugs. International Journal of Unani and Integrative Medicine. 4: 22-25.


GUEST EDITOR OF THE JOURNALS:
• Special Editor for ‘Molecular Signaling During Communicable and Non-communicable Diseases’, Journal Current Pharmaceutical Design, Bentham Science, Impact Factor 3.11.
• Guest Editor for MicroRNAs and Immunity, Journal Seminars in Cell and Developmental Biology, Elsevier, Impact Factor 7.7.

Honours and Awards:
1. Scientist of the Year Award for 2015 by National Environment Science Academy, New Delhi, India.
2. DBT Post-doctoral Fellowship (July 2007-Aug2010) for the project entitled “Cloning and Functional Characterization of Rice Calnexin and its Interaction with Other Proteins”.
3. Nominated for Dr. C. R. Krishnamurthy Young Scientist Award (2008).
4. Junior Research Fellowships (2001-2003) from Department of Biotechnology (DBT), Govt. of India.
5. Vice Chancellor’s Merit scholarship in two years of postgraduation (1998-2000)

Travel Awards:

1. 1. Travel Grant from Amity University for International Conference at Paris, France (2019)
2. Travel Grant from the organizers of BIOCON-2019, United Scientific Group, International Conference at Paris, France (2019)
3. Travel Grant from CSIR for International Conference at Versailles, France (2013)
4. Travel Grant from Indian National Science Academy (INSA) for International Conference at Versailles, France (2013)
5. Travel Grant from DST for International Conference at Versailles, France (2013)
6. Travel Grant from Amity University for presenting research work at Versailles, France (2013).
7. Travel Grant from CSIR for presenting research work in International Conference at Vienna, Austria (2012).
8. Travel Grant from Indian National Science Academy (INSA) for presenting research work at Vienna, Austria (2012).
9. Travel Grant from Amity University for presenting research work at Vienna, Austria (2012).
10. Travel Grant from DST for presenting research work International Conference at Prague, Check Republic (2010).
11. Travel Grant from DBT for presenting research work at Prague, Check Republic (2010).
12. Travel Grant from Society of Experimental Biology, U.K. for presenting research work at Prague, Check Republic (2010).

Reviewer of the Scientific Journals
1. Journal of Hepatocellular Carcinoma, Taylor and Francis, (Impact Factor 4.9)
2. Cell Cycle, Taylor and Francis, (Impact Factor 5.1)
3. IBRO Neuroscience Reports (Elsevier)
4. PLOS ONE (supports DORA)
5. Cell Biology and Toxicology, Spinger (Impact Factor 6.6)
6. All Life, Taylor and Francis (Impact Factor 4.88)
7. Saudi Journal of Biological Sciences, Elsevier (Impact Factor 4.2)
8. Metabolic Brain Disease, Springer (Impact Factor 3.58)
9. Plant Cell and Environment, Wiley (Impact Factor 6.16)
10. Critical Reviews in Biotechnology, Taylor and Francis (Impact Factor 7.51)
11. Scientific Reports (Nature publishing group) Impact Factor 4.2
12. The American Journal of the Medical Sciences (Impact Factor 2.37)
13. Environmental and Experimental Botany, Elsevier (Impact Factor 4.3)
14. Gene, Elsevier (Impact Factor 2.3)
15. Molecular Biology Reports, Springer (Impact Factor 1.8)
16. Proceedings of the National Academy of Sciences, India, Springer (Impact Factor 0.396)
17. Indian Journal of Medicinal Plants
18. Annual Review and Research in Biology
19. Biochemical Sciences
20. Journal of Pharmacognosy and Phytochmistry
• Presently working as Full Professor from September 2010 till date at Amity University, NOIDA.
• Ph.D. from Jamia Hamdard University
• Postdoctoral Research from International Centre for Genetic Engineering and Biotechnology (ICGEB).
• Published 90 papers in international journals, Cumulative impact factor is 230.
• Published 7 books with international publishers Elsevier-UK, Springer Nature Germany and Taylor and Francis
• Total citations of my publications: 3200.
• h-index is 23 and i-10 index is 39.
• Presented research work in international conferences at Prague, Germany, and France.
• Got travel assistantship from Government of India (DST, DBT, SERB, INSA, CSIR), Amity University, International Agencies (Society of Experimental Biology, UK and United Scientific Group, USA).
• SCIENTIST OF THE YEAR award by National Environment Science Academy (NESA).
• Vice Chancellor’s Merit Scholarship.
• Nominated for Dr. C. R. Krishnamurthy Young Scientist Award.
• DBT, Govt. of India Post-doctoral Fellowship (July 2007-Aug2010)
• DBT, Govt. of India JRF (2001-2003)
• Guiding 6 Ph.D. students and successfully guided 10 Master students for research thesis.
• Filed three patents.
• Successfully completed four research projects from DBT, SERB and AYUSH as Principal investigator (PI) worth 1 crore, 23 lakh rupees.
• Three ongoing research projects from Govt. of India (1 crore rupees).
• Guest editor of the special issue for Current Pharmaceutical Design (Impact Factor 3.2) and Seminars in Cell and Development Biology (Impact Factor 7.7).
• Reviewer and editorial board member of more than 25 international journals.
PHARMACY
Amity University Noida UP