PUBLICATIONS

Publications

a. Name of the Faculty member: Prof Bhudev C Das

b. Total Research Publications - last 5 years

1. Jaiswal SR, Agarwal M, Bhagawati G, Das BC, Baligar P, Garg M, Biswas S, Chakrabarti S. Long Term Follow-Up Of Abatacept, Post-Transplantation Cyclophosphamide and Sirolimus (AbaCyS) based Haploidentical Transplantation in Younger Patients with Nonmalignant Diseases. Transplantation and Cellular Therapy. 2024 Mar 13.
2. Gupta S, Kumar P, Das BC: Challenges and opportunities to making Indian women cervical cancer free. Indian Journal of Medical Research 2023, 158(5&6):470-475.
3. Kumar P, Gupta S, Das BC: Saliva as a potential non-invasive liquid biopsy for early and easy diagnosis/prognosis of head and neck cancer. Translational Oncology 2024, 40:101827.
4. Rana A, Adhikary M, Singh PK, Das BC, Bhatnagar S: “Smart” drug delivery: A window to future of translational medicine. Frontiers in Chemistry 2023, 10.
5. Sahu RK, Kumar B, Singh R, Kumari S, Tandon S, Das BC, Hedau ST: Schleichera oleosa Seed Extract Reduced the Proliferation of Breast Cancer by Regulating the BRCA1 and p16 Genes. Asian Pacific Journal of Cancer Prevention 2022, 23(1):151-160.
6. Mukherjee Das A, Gogia A, Janardhanan R, Babu-Rajendran R, Das BC: Environmental Contamination and Chronic Exposure to Endocrine-Disrupting Phthalates: An Overlooked and Emerging Determinant for Hormone-Sensitive Cancers. Journal of the Indian Institute of Science 2022, 102(2):731-742.
7. Mukherjee Das A, Gogia A, Garg M, Elaiyaraja A, Arambam P, Mathur S, Babu-Rajendran R, Deo SVS, Kumar L, Das BC et al: Urinary concentration of endocrine-disrupting phthalates and breast cancer risk in Indian women: A case-control study with a focus on mutations in phthalate-responsive genes. Cancer Epidemiology 2022, 79.
8. Lone SN, Bhat AA, Wani NA, Karedath T, Hashem S, Nisar S, Singh M, Bagga P, Das BC, Bedognetti D et al: miRNAs as novel immunoregulators in cancer. Seminars in Cell and Developmental Biology 2022, 124:3-14.
9. Kirtonia A, Ashrafizadeh M, Zarrabi A, Hushmandi K, Zabolian A, Bejandi AK, Rani R, Pandey AK, Baligar P, Kumar V et al: Long noncoding RNAs: A novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia. Journal of Cellular Physiology 2022, 237(1):450-465.
10. Khan A, Das BC, Abiha U, Sisodiya S, Chikara A, Nazir SU, Das AM, Rodrigues AG, Passari AK, Tanwar P et al: Insights into the role of complement regulatory proteins in HPV mediated cervical carcinogenesis. Seminars in Cancer Biology 2022, 86:583-589.
11. Hussain S, Rani J, Tulsyan S, Sisodiya S, Chikara A, Nazir SU, Srivastava A, Khan A, Dash NR, Saraya A et al: Influence of HPV infection in esophageal cancer: A systematic review and meta-analysis. Gene Reports 2022, 28.
12. Fan W, Yu M, Wang X, Xie W, Tian R, Cui Z, Jin Z, Huang Z, Das BC, Severinov K et al: Non-homologous dsODN increases the mutagenic effects of CRISPR-Cas9 to disrupt oncogene E7 in HPV positive cells. Cancer Gene Therapy 2022, 29(6):758-769.
13. Basu N, Narad P, Guptasarma ML, Tandon C, Das BC, Tandon S: Computational and in Vitro Approaches to Elucidate the Anti-cancer Effects of Arnica montana in Hormone-Dependent Breast Cancer. Homeopathy 2022, 111(4):288-300.
14. Basu N, Garg M, Tandon C, Das BC, Tandon S: Arsenicum album Induces Cell Cycle Arrest and Apoptosis, and Inhibits Epithelial-Mesenchymal Transition in Hormone-Dependent MCF7 Breast Cancer Cells. Homeopathy 2022, 112(3):160-169.
15. Raj S, Khurana S, Choudhari R, Kesari KK, Kamal MA, Garg N, Ruokolainen J, Das BC, Kumar D: Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy. Seminars in Cancer Biology 2021, 69:166-177.
16. Merarchi M, Dudha N, Das BC, Garg M: Natural products and phytochemicals as potential anti-SARS-CoV-2 drugs. Phytotherapy Research 2021, 35(10):5384-5396.
17. Gupta S, Kumar P, Das BC: HPV+ve/−ve oral-tongue cancer stem cells: A potential target for relapse-free therapy. Translational Oncology 2021, 14(1).
18. Gupta S, Kumar P, Das AM, Gupta DK, Das BC: Human viruses: Infection, prevention and potential target(s) for therapy - a comprehensive review. In: Human Viruses: Diseases, Treatments and Vaccines: The New Insights. edn.; 2021: 3-54.
19. Das AM, Das BC: Exposure to endocrine-disrupting chemicals in utero and thyroid cancer risk in offspring. The Lancet Diabetes and Endocrinology 2021, 9(5):255.
20. Cui Z, Liu H, Zhang H, Huang Z, Tian R, Li L, Fan W, Chen Y, Chen L, Zhang S et al: The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy. Molecular Therapy - Nucleic Acids 2021, 26:1466-1478.
21. Aftab M, Poojary SS, Seshan V, Kumar S, Agarwal P, Tandon S, Zutshi V, Das BC: Urine miRNA signature as a potential non-invasive diagnostic and prognostic biomarker in cervical cancer. Scientific Reports 2021, 11(1).
22. Aftab M, Ghufran M, Kumar D, Das BC: In silico analysis of the role of hsa-mir-155-5p in cervical cancer. Chemical Biology Letters 2021, 8(3):94-105.
23. Niu G, Jin Z, Zhang C, He D, Gao X, Zou C, Zhang W, Ding J, Das BC, Severinov K et al: An effective vaginal gel to deliver CRISPR/Cas9 system encapsulated in poly (β-amino ester) nanoparticles for vaginal gene therapy. EBioMedicine 2020, 58.
24. Kirtonia A, Pandya G, Sethi G, Pandey AK, Das BC, Garg M: A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia. Journal of Molecular Medicine 2020, 98(8):1069-1091.
25. Gao X, Jin Z, Tan X, Zhang C, Zou C, Zhang W, Ding J, Das BC, Severinov K, Hitzeroth II et al: Hyperbranched poly(β-amino ester) based polyplex nanopaticles for delivery of CRISPR/Cas9 system and treatment of HPV infection associated cervical cancer. Journal of Controlled Release 2020, 321:654-668.
26. Chen Y, Jiang H, Wang T, He D, Tian R, Cui Z, Tian X, Gao Q, Ma X, Yang J et al: In vitro and in vivo growth inhibition of human cervical cancer cells via human papillomavirus E6/E7 mRNAs’ cleavage by CRISPR/Cas13a system. Antiviral Research 2020, 178.
27. Chandel V, Raj S, Kumar P, Gupta S, Dhasmana A, Kesari KK, Ruokolainen J, Mehra P, Das BC, Kamal MA et al: Metabolic regulation in HPV associated head and neck squamous cell carcinoma. Life Sciences 2020, 258.
28. Basu N, Das BC, Tandon S: Interim Management of COVID-19 by Repurposed Homeopathic Medicines. Homeopathy 2020, 109(3):182-183.

b. Funded research project of last 5 years with completion date - Govt. & Industry

1	Identification of specific small peptide inhibitors binding to G-quadruplex motifs of cellular and viral protooncogenes and telomeric sequences in cancer cells for therapeutic intervention	Dr. B. C. Das (Co-PI)	DBT	5249219.00	01-Jun-2018	01-Jun-2021
2	Assessment of human papillomavirus (HPV) infection status and genotype among women and adolescents of Sikkim (AHPV-SGS)	NCD/NER/05/2017-18	ICMR	2500000.00	01-Jan-2018	31-Dec-2022
3	Development of Novel Curcumin-Folate-Drug Conjugates for Targeted delivery of Drug and Curcumin together to cancer and Cancer Stem Cells for Effective treatment	5/13/15/2015/NCD-III	ICMR	6840000.00	01-Apr-2016	31-Mar-2022
4	Analysis of key gene mutations and miRNAs and their interaction with Fos-related antigen 1/2 (Fra 1/2) to identify therapeutic targets in triple-negative breast cancer stem cells	5/13/03/2019-NCD-III	ICMR	8000000.00	02-Sep-2019	01-Sep-2022

c. Details of Commercialization / Technology transfer, if any: None

d. Patent / Copyright, if any:

1. Patent No 439723 1112/DEL/2015 Grant date 20/07/2023 A method for the synthesis of a novel bioconjugate drug for targeted treatment of cancer and cancer stem cells Inventors Seema Bhatnagar, Abhilash Rana Prabhat Kumar Bhudev C Das

a. Name of the Faculty member: Prof Subhrajit Biswas

1. b) Total Research Publications - last 5 years
2. S Ghose, S Roy, V Ghosh, SK. Sharawat, R Pramanik, S Biswas, and A Biswas (2024) The plasma EBV DNA load with IL-6 and VEGF levels as predictive and prognostic biomarker in nasopharyngeal carcinoma Virol J. 2024; 21: 224 doi: 10.1186/s12985-024-02473-0 IF:3.6
3. S Upreti, P Sharma, S Biswas, MP Ghosh. (2024) Coenzyme Q10 Induces Apoptosis in Human Retinoblastoma Cells by Downregulating Vascular Endothelial Growth Factor. Scientific Report (Accepted) Manuscript ID no.: 285acb0d-ea6e-4599-a870-702e37bc4d7
4. N Nautiyal, D Maheshwari, D Kumar, EP Rao DM Tripathi, S Kumar, S Diwakar, M Bhardwaj, S Mohanty, P Baligar, A Parasar, C Bihari, S Biswas, S.K Sarin, A. Kumar (2024) Rejuvenating bone marrow hematopoietic reserve prevents regeneration failure and hepatic decompensation in animal model of cirrhosis. Frontiers in Immunology., 2024. Volume 15 - 2024 | https://doi.org/10.3389/fimmu.2024.1439510. IF:5.6
5. N Sharma, M Gupta, P Anand, Y Akhter, N Al-Dayan, HA Majed, S Biswas, S Ali, M Sarwat (2024) Mechanistic Insight into the Autophagic and Apoptotic Activity of Kaempferol on Liver Cancer Cells. Onco Targets and Therapy https://doi.org/10.2147/OTT.S460359 2024:17 p579–601 IF: 4.3
6. Anjali Saxena and, S Biswas and B Saha (2024) Deciphering the Biological Assays to Elucidate the Potential of Bioactive Molecules. http://dx.doi.org/10.2139/ssrn.4840341. Heliyon (PrePrint) IF: 3.4
7. SR Jaiswal, M Agarwal, G Bhagawati, BC Das, P Baligar, M Garg, S Biswas, S Chakrabarti (2024) Long Term Follow-Up of Abatacept, Post-Transplantation Cyclophosphamide and Sirolimus (AbaCyS) based Haploidentical Transplantation in Younger Patients with Nonmalignant Diseases. Transplantation and Cellular Therapy, Mar 13: S2666-6367(24)00260-4. PMID: 38490295 doi: 10.1016/j.jtct.2024.03.010. IF: 3.5
8. S Sharma, SM Ghufran, M Aftab, C Bihari, S Ghose, S Biswas* (2024) Survivin inhibition ameliorates liver fibrosis by inducing hepatic stellate cell senescence and depleting hepatic macrophage population. Journal of Cell Communication and Signalling e12015 Online version Jan 25 doi.org/10.1002/ccs3.12015. IF: 5.9
9. SR Jaiswal, M Agarwal, BC Das, P Baligar, S Biswas, S Chakrabarti (2024) Abatacept Augments Natural Killer Cell Cytotoxicity in Haploidentical HCT: A Novel Approach for Separating GVL and Gvhd. Transplantation and Cellular Therapy February 2024 Volume 30, Issue 2, Pages S311-S312 doi.org/10.1016/j.jtct.2023.12.428 IF: 3.5
10. N Nautiyal, D Maheshwari, DM Tripathi, D Kumar, EP Rao, S Yadav, S Diwakar, M Bhardwaj, S Mohanty, P Baligar, A Parasar, C Bihari, S Biswas, R Maiwall, S.K Sarin, A. Kumar (2024) Early loss of bone marrow hematopoietic stem cells drives regeneration failure during cirrhosis; Scientific Reports -Nature (in revision) doi.Org/10.21203/rs.3.rs-3250973/v1. IF:4.9
11. N Sharma, M Gupta, G Nabi, S Biswas, S Ali, M Sarwat (2023) Variation in the anti-oxidant, anti-obesity, and anti-cancer potential of different polarity extracts of saffron petals. 3 Biotech. 2023 Jul;13(7):249. doi: 10.1007/s13205-023-03669-x. Epub 2023 Jun 25. IF: 3.1
12. Ghufran SM, Sharma P, Roy B, Jaiswal S, Aftab M, Sengupta S, Ghose S, Biswas S*. (2023) Transcriptome wide functional analysis of HBx expressing human hepatocytes stimulated with endothelial cell cross-talk. Genomics. Jul;115(4):110642. Epub 2023 May 18. PMID: 37209778. doi: 10.1016/j.ygeno.2023.110642. IF: 4.5
13. Ghufran SM, Sharma S, Ghose S, Biswas S* (2022) Divergent effect of Birinapant, and BV6 SMAC mimetic on TNFα induced NF-κBsignaling and cell viability in activated hepatic stellate cells. Mol Biol Rep. 2022 Dec 21. doi: 10.1007/s11033-022-08210-6. Online ahead of print. PMID: 36542236
14. Mukherjee I, Biswas S, Singh S, Talukdar J, Alqahtani MS, Abbas M, Nag TC, Mridha AR, Gupta S, Sharma JB, Kumari S, Dhar R, Karmakar S. (2023) Monosodium Glutamate Perturbs Human Trophoblast Invasion and Differentiation through a Reactive Oxygen Species-Mediated Pathway: An In-Vitro Assessment. Antioxidants (Basel). 2023 Mar 3;12(3):634. doi: 10.3390/antiox12030634. IF: 7.0
15. Mukherjee I, Singh S, Karmakar A, Kashyap N, Mridha AR, Sharma JB, Luthra K, Sharma RS, Biswas S, Dhar R, Karmakar S (2023). New immune horizons in therapeutics and diagnostic approaches to Preeclampsia. Am J Reprod Immunol. 2023 Feb;89(2):e13670. doi: 10.1111/aji.13670. Epub 2023 Jan 2. PMID: 36565013 IF: 3.8
16. Jaiswal SR, Saifullah A, Arunachalam J, Lakhchaura R, Tailor D, Mehta A, Bhagawati G, Aiyer H, Biswas S, Khamar B, Malhotra SV, Chakrabarti S (2023). Augmenting Vaccine Efficacy against Delta Variant with 'Mycobacterium-w'-Mediated Modulation of NK-ADCC and TLR-MYD88 Pathways. Vaccines (Basel). 2023 Feb 1;11(2):328. doi: 10.3390/vaccines11020328. IF: 7.8
17. Hasan AH, Shakya S, Hussain FHS, Murugesan S, Chander S, Pratama MRF, Jamil S, Das B, Biswas S, Jamalis J (2023) Design, synthesis, anti-acetylcholinesterase evaluation and molecular modelling studies of novel coumarin-chalcone hybrids. J Biomol Struct Dyn. 2023 Jan 2:1-13. doi: 10.1080/07391102.2022.2162583. PMID: 36591704 IF: 4.4
18. Sengupta S, Ghufran SM, Khan A, Biswas S, Roychoudhury S. (2023) Transition of amyloid/mutant p53 from tumor suppressor to an oncogene and therapeutic approaches to ameliorate metastasis and cancer stemness. Cancer Cell Int. 2022 Dec 26;22(1):416. doi: 10.1186/s12935-022-02831-4. IF: 6.4
19. Gupta M, Ghufran SM, Kausar T, Ali R, Biswas S, Nayeem SM, Ishrat R, Ali S, Ahmad A, Rather IA, Sarwat M. (2022) Z-Guggulsterone Is a Potential Lead Molecule of Dawa-ul-Kurkum against Hepatocellular Carcinoma. Molecules. 2022 Aug 11;27(16):5104. IF: 5.0
20. A Agarwal, S Jeevanandham, C Kar, MP Rai, V Kumar, H B. Bohidar, S Biswas and M Mukherjee (2022) Crystalline Domains Nested on Two-Dimensional Nanosheets as Heterogeneous Nanomachineries for the Sustainable Production of Bioactive Compounds from Chlorella sorokiniana. ACS Sustainable Chem. Eng. 2022, 10, 30, 9732–9748doi.org/10.1021/acssuschemeng.2c00861 IF: 9.2
21. Ghufran S M, Sharma S, Ghose S, Biswas S* (2022). Context-dependent interplay of p53 during interaction of hepatocellular carcinoma and endothelial cells. Microvascular Research. 2022 Jul; 142:104374. doi: 10.1016/j.mvr.2022.104374. IF: 3.5
22. Nautiyal N, M Deepanshu, E Rao, S Mohanty, A Parasar, C Bihari, S Biswas et al (2022) Restoring bone marrow hematopoietic stem cells (BM-HSC) reserve augments regression of fibrosis and regeneration in animal model of cirrhosis. Journal of Hepatology 77: S756 DOI:10.1016/S0168-8278(22)01828-1
23. Roy B, Ghose S, Biswas S* (2022). Therapeutic strategies for miRNA delivery to reduce hepatocellular carcinoma. Seminars in Cell & Developmental Biology26:S1084-9521(21)00079-3. doi: 10.1016/j.semcdb.2021.04.006. IF: 6.69
24. Hasan AH, Murugesan S, Amran SI, Chander S, Alanazi MM, Hadda TB, Shakya S, Pratama MRF, Das B, Biswas S, Jamalis (2022) Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and molecular dynamics simulation. J. Bioorg Chem. 2022 Feb;119:105572. doi: 10.1016/j.bioorg.2021.105572. Epub 2021 Dec 21. PMID: 34971946
25. S Sharma, MS Ghufran, B Das, B Roy, S. Ghose, S Biswas*(2021). Survivin expression is essential for early activation of hepatic stellate cells and fibrosis progression in chronic liver injury. Life Sciences- Elsevierdoi.org/10.1016/j.lfs.2021.120119 IF: 5.037
26. Nautiyal N, Maheshwari D, Kumar D, Kumari R, Parasar A, Sharma S, Bihari C, Biswas S et al, (2021) Establishment of murine model of Acute-on-Chronic Liver Failure with renal failure. Hepatology international doi: 10.1007/s12072-021-10244-0 IF: 6.048
27. I Mukherjee, R Dhar, S Singh, J B Sharma, T C Nag, A R Mridha, P Jaiswal S Biswas*, S Karmakar (2021) Oxidative stress-induced impairment of trophoblast function causes Preeclampsia through the unfolded protein response pathway. Scientific Report-Nature 16;11(1):18415. doi: 10.1038/s41598-021-97799-y IF: 5.133
28. N Sharma, S Biswas, N Al-Dayan AS Alhegailiand M Sarwat (2021) Antioxidant Role of Kaempferol in the Management of Hepatocellular Carcinoma. Antioxidants 10(9):1419. doi: 10.3390/antiox10091419 IF: 6.312
29. S Sharma MS Gufran, S Ghose, C. Bihari, S Biswas* (2021). Survivin inhibition ameliorates liver fibrosis via inducing senescence in hepatic stellate cells. Journal of Hepatology–Elsevier 2021 vol. 75(2) | S389 IF: 25.7
30. Sharma S, Ghufran S M, Ghose S, Biswas S* (2021). Cytoplasmic vacuolation with endoplasmic reticulum stress directs sorafenib induced non-apoptotic cell death in hepatic stellate cells Scientific Report- Nature11: 3089: IF: 5.133
31. Tayal N, Ghufran SM, Srivastava P, Kandhwal S, Biswas S and Srivastava N. Anti-Angiogenic Activity of Columbin: A Diterpenoid from Tinospora Cordifolia. IJBPAS (2020) 9(3): 540-552 IF: 3.8
32. Nautiyal N, M Deepanshu, D Kumar, R Kumari, A Parasar, C Bihari, S Biswas et al Establishment of murine model of acute-on-chronic liver failure. (2020) Journal of Hepatology –Elsevier 73, S296-S297 IF 25.7
33. S. Biswas* (2020) A Rethink on Survivin: in prospective of reproductive health. ISSRF Issue 24 p 47-49 ISSN 2395-2806
34. Shakeel A, Bhattacharya R, Jeevanandham S, Kochhar D, Singh A, Mehra L, Ghufran M, Garg P, Sangam S, Biswas S et al (2019) Graphene Quantum Dots in the Game of Directing Polymer Self-Assembly to Exotic Kagome Lattice and Janus Nanostructures. ACS Nano. 13(8):9397-9407. ISSN: 1936-0851 IF: 15.88
35. S Sharma, S M Ghufran, S Biswas* (2018). Strategies of antagonizing anti-apoptotic proteins to target detrimental cells for regression of liver injuries and carcinogenesis Cancer Medicine Vol 7, S1, p 73 onlinelibrary.wiley.com/journal/20457634 IF: 3.8
36. S Ghose*, S Biswas*, Kasturi Datta, Rakesh K. Tyagi (2018) Dynamic Hyaluronan drives liver endothelial cells towards angiogenesis. BMC Cancer18:648 IF: 4.4
37. A Varshney, JJ. Panda, AK. Singh, N. Yadav, C. Bihari, S Biswas, SK. Sarin, VS. Chauhan (2018).Targeted delivery of miR-199a-3p using self-assembled dipeptide nanoparticles efficiently reduces hepatocellular carcinoma. Hepatology 67, 1392-1407: IF: 17.42
38. S Biswas* and S. Ghose (2018). Divergent impact of Gender in Advancement of Liver injuries, diseases, and carcinogenesis. Frontier in Biosciences.10:65-100. IF: 3.5
39. S Sharma, S M Ghufran, S Biswas* (2018). Survivin inhibition limits TGF-β-induced fibrogenic responses of hepatic stellate cells. onlinelibrary.wiley.com/journal/20457634 Cancer Medicine Vol 7, S1, p 46 IF: 3.8
40. c) Funded research project of last 5 years - Govt. & Industry - completed & ongoing, along with starting & completion date.

2024-2027 Ongoing Extramural Research Project as Principal investigator (PI) from from Science and Engineering Research Board (SERB), India (2024) entitled “Therapeutic Target of Yes Associated Protein (YAP) signaling in tumor microenvironment of hepatocellular carcinoma by inhibiting stromal cell secretory networks” CRG/2018/006978: 64 Lakhs (SERB-AUUP-Recently approved)

2021-2024 Ongoing Extramural Research Project as Co-Principal investigator (PI) from Department Health Research-Indian Council of Medical Research (DHR-ICMR), India (2020) entitled “Bio-evaluation and Identification of Lead Molecules for Lung and Colon cancer from Selected Medicinal Plants” GIA/2019/001026/PRCGIA: 47 Lakhs

2019-2023 Completed Extramural Research Project as Principal investigator (PI) from Indian Council of Medical Research (ICMR), India (2019) entitled “Translational approach to inhibit hepatoma cell stemness by altering survival signals to prevent recurrence of carcinogenesis” 2019-1306/5CR/ADHOC-BMS: 73 Lakhs (ICMR-AUUP-502)

2019-2023 Completed Extramural Research Project as Principal investigator (PI) from Science and Engineering Research Board (SERB), India (2019) entitled “Translational approach for reducing Hepatocellular Carcinoma through modulation of extracellular matrix protein Lysyl Oxidase (LOX) in tumor microenvironment” CRG/2018/003918: 63 Lakhs (SERB-AUUP-503)

2019-2024 Completed DST R & D Infrastructure Scheme as Principal Project Coordinator: FIST Life Science Level I or II (SR/FST/LS-II/2017/115) Department of Science & Technology (DST): 1.38 Crores (DST-AUUP-452)

2024-2027 Ongoing Extramural Research Project as Co-Principal investigator (PI) from from Science and Engineering Research Board (SERB), India (2024) entitled “Investigating the role of p53 amyloid in the tumor associated macrophage polarization and tumor microenvironment of colorectal carcinoma” 80 Lakhs

2023-2026 Ongoing Extramural Research Project as Co-Principal investigator (PI) from Indian Council of Medical Research (ICMR), India (2024) entitled “Breaking plasticity of CCL18/CD163+ Tumor associated macrophages for improving response of refractory cases of Chronic Myeloid Leukemia towards chemotherapy” 37 Lakhs

2024-2027 Ongoing Extramural Research Project as Co-Principal investigator (PI) from from Science and Engineering Research Board (SERB), India (2024) entitled “Understanding the protective effect of chlorogenic acid in rat embryonic neural stem cells prenatally exposed to air particulate matter: A transcriptome-based approach” 52 Lakhs

1. d) Details of Commercialization / Technology transfer, if any NA
2. e) Patent / Copy right, if any

• A Varshney, J Panda, A K. Singh, SB. Rooge, SK. Sarin, VS. Chauhan, S Biswas* (2023) Dipeptide based Nanostructures for Targeted Delivery of miRNA for HCC treatment. Granted Patent Number 453925 Application No. 01611023040.
• S Sharma, C Shandilya1, S.M. Ghufran1, S. Ghose2, S. Biswas* SMAC mimetic as a potential therapeutic agent to regress liver cirrhosis and hepatocellular carcinoma by suppressing activated hepatic stellate cells. Ref. No. 201611025632; Application number: 202211073900 dated 19-12-2023
• N Sharma, M Sarwat & S. Biswas*. A formulation for anticancer activity of a byproduct of saffron, the flower petals and method thereof. Ref. No. 201611025632; Application number E-91/15597/2021/DEL dated 04.08.2021

Name of the Faculty member: Prof. Simran Tandon

1. b) Total Research Publications - last 5 years

1. Sahu, R.K., Tandon, S., Singh, S. et al. Methyl CpG binding protein MBD2 has a regulatory role on the BRCA1 gene expression and its modulation by resveratrol in ER+, PR+ & triple-negative breast cancer cells. BMC Cancer 2024,24, 566 (IF-3.8). https://doi.org/10.1186/s12885-024-12274-
2. Nayak D ,Varanasi R, Sinha A, Manchanda RK, Janardhanan R, Tandon S, Pati S Incidence of acute undifferentiated febrile illnesses in an urban slum of Delhi: A longitudinal cohort study. Clinical Epidemiology and Global Health.2024 Volume 26,2024,101550,https://doi.org/10.1016/j.cegh..101550
3. Varanasi R, Sinha A, Nayak D, Manchanda RK, Janardhanan R, Tandon S, Pati S. Prevalence and correlates of multimorbidity among patients attending AYUSH primary care settings in Delhi-National Capital Region, India. BMC Complement Med Ther. 2023 Nov 29;23(1):429. doi: 10.1186/s12906-023-04158-7. PMID: 38031066. (IF-3.9)
4. Khan S, Baligar P, Tandon C, Nayyar J, Tandon S. Molecular heterogeneity in prostate cancer and the role of targeted therapy. Life Sci. 2023 Nov 17;336:122270. doi: 10.1016/j.lfs.2023.122270. Epub ahead of print. PMID: 37979833.(IF-6.78)

1. Kumari K, Tandon S, Ghosh S, Baligar P. Gelatin scaffold ameliorates proliferation & stem cell differentiation into the hepatic like cell and support liver regeneration in partial-hepatectomized mice model. Biomed Mater. 2023 Nov 1;18(6). doi: 10.1088/1748-605X/ad04fd. PMID: 37860885.(IF-4.0)
2. Basu N, Tandon C, Tandon S Anti-Epithelial-Mesenchymal Transition Property of Arnica montana Attributed to Mitochondria-Mediated Apoptosis in Triple-Negative Breast Cancer.Biointerface Research in Applied Chemistry,2023,13(5) 7342-7355
3. Basu N, Garg M, Tandon C, Das BC, Tandon S. Arsenicum album Induces Cell Cycle Arrest and Apoptosis, and Inhibits Epithelial-Mesenchymal Transition in Hormone-Dependent MCF7 Breast Cancer Cells. Homeopathy Homeopathy. 2023 Aug;112(3):160-169. doi: 10.1055/s-0042-1755364. Epub 2022 Nov 28. PMID: 36442592.. (IF 1.7)
4. Basu N, Narad P, Guptasarma ML, Tandon C, Das BC, Tandon S. Computational and In Vitro Approaches to Elucidate the Anti-cancer Effects of Arnica montana in Hormone-Dependent Breast Cancer. Homeopathy. 2022 Jul 5. doi: 10.1055/s-0042-1743565. Epub ahead of print. PMID: 35790192.(IF 1.7)
5. Sahu RK, Verma VV, Kumar A, Tandon S, Chandra Das B, Hedau ST. In silico prediction and interaction of resveratrol on methyl-CpG binding proteins by molecular docking and MD simulations study. RSC Adv. 2022 Apr 13;12(18):11493-11504. doi: 10.1039/d2ra00432a. PMID: 35425086; PMCID: PMC9006347. (IF 4.03)

1. Singh A, Tandon S, Kumar D ,Kaur T, Kesari K,Tandon C.Insights into the cytoprotective potential of Bergenia ligulata against oxalate‑induced oxidative stress and epithelial–mesenchymal transition (EMT) via TGFβ1/p38MAPK pathway in human renal epithelial cells. Urolithiasis. https://doi.org/10.1007/s00240-022-01315-4 (IF 3.426)
2. Sahu, R.K. ,Kumar, B., Singh, R. ,Kumari, S. , Tandon, S. ,Das, B.C., Hedau, S.T Schleichera oleosa Seed Extract Reduced the Proliferation of Breast Cancer by Regulating the BRCA1 and p16 Genes. Asian Pacific Journal of Cancer Prevention, 2022,23(1)151-160 (IF 1.89)
3. Singh A, Tandon S, Kaur T, Tandon C.In vitro Studies on Calcium Oxalate Induced Apoptosis Attenuated by Didymocarpus pedicellate. Biointerface Research in Applied Chemistry,2022,12(6) 7342-7355 (IF 1.94)
4. Pandya G, Kirtonia A, Singh A,Goel A, Chakrabhavi DM, Kanchugarakoppal R, Pandey AK, Sonia Kapoor S, Tandon S, Sethi G, Garg M..A comprehensive review of the multifaceted role of the microbiota in human pancreatic carcinoma. Seminars in Cancer Biology,2021,ISSN 1044-579X,https://doi.org/10.1016/j.semcancer.2021.05.027 (IF 15.7)
5. Khan S, Suryavanshi M, Kaur J, Nayak D, Khurana A, Manchanda RK, Tandon C, Tandon S. Stem cell therapy: A paradigm shift in breast cancer treatment.World J Stem Cells. 2021 Jul 26;13(7):841-860. doi: 10.4252/wjsc.v13.i7.841(IF 5.4)

1. Aftab M,. Poojary S, Seshan V, Kumar S, Agarwal P, Tandon S, Zutshi V & Das BC. Urine miRNA signature as a potential non-invasive diagnostic and prognostic biomarker in cervical cancer. Sci Rep 2021 ,11, 10323 (IF 4.99)
2. Singh A, Tandon S, Nandi SP, Kaur T, Tandon C. Downregulation of inflammatory mediators by ethanolic extract of Bergenia ligulata (Wall.) in oxalate injured renal epithelial cells. J Ethnopharmacol. 2021 Apr 6:114104. doi: 10.1016/j.jep.2021.114104. Epub ahead of print. PMID: 33836258(IF 5.19)
3. Bano S, Tandon S, Tandon C. Emerging role of exosomes in arterial and renal calcification. Hum Exp Toxicol. 2021 Mar 19:9603271211001122. doi: 10.1177/09603271211001122. (IF 3.247)
4. Singh A, Tandon S, Tandon C. An update on vascular calcification and potential therapeutics. Mol Biol Rep. 2021 Jan 4. doi: 10.1007/s11033-020-06086-y. (IF 2.742)
5. Kumar D, Baligar P, Srivastav R, Narad P, Raj S, Tandon C, Tandon S. Stem Cell Based Preclinical Drug Development and Toxicity Prediction. Current Pharmaceutical Design 2020:26: 1. https://doi.org/10.2174/1381612826666201019104712(IF 3.31)
6. Narula S, Tandon S, Kumar D, Varshney S, Adlakha K, Sengupta S, Singh SK, Tandon C. Human kidney stone matrix proteins alleviate hyperoxaluria induced renal stress by targeting cell-crystal interactions. Life Sci. 2020 Dec 1;262:118498. doi: 10.1016/j.lfs.2020.118498. Epub 2020 Sep 28.(IF 6.78)
7. Khan S, Nayak D, Khurana A, Manchanda RK, Tandon C, Tandon S. In Vitro Assessment of Homeopathic Potencies of Hydrastis canadensis on Hormone-Dependent and Independent Breast Cancer. Homeopathy 2020:DOI: 10.1055/s-0040-1709668 (IF 1.44)
8. Basu N, Das BC, Tandon S. Interim Management of COVID-19 by Repurposed Homeopathic Medicines. Homeopathy 2020: DOI: 10.1055/s-0040-1713004 (IF 1.44)
9. Suryavanshi M, Jaipuria J, Mehta A, Kumar D, Panigrahi MK, Verma H, Saifi M, Sharma S, Tandon S, Doval DC, Das BC. Droplet digital polymerase chain reaction offers an improvisation over conventional immunohistochemistry and fluorescent in situ hybridization for ascertaining Her2 status of breast cancer. South Asian J Cancer. 2019 Oct-Dec;8(4):203-210. doi: 10.4103/sajc.sajc_344_18
10. Kaushik J, Tandon S, Bhardwaj R, Kaur T, Singla SK, Kumar J, Tandon . Delving into the Antiurolithiatic Potential of Tribulus terrestris Extract Through -In Vivo Efficacy and Preclinical Safety Investigations in Wistar Rats. Sci Rep. 2019 Nov 4;9(1):15969. doi: 10.1038/s41598-019-52398-w (ISSN 20452322)(IF 4.37)
11. Behl K, Joshi M, Sharma M, Tandon S,Chaurasia A, Bhatnagar A, Nigam S. Performance evaluation of isolated electrogenic microalga coupled with graphene oxide for decolorization of textile dye wastewater and subsequent lipid production. Chem. Engg. J. 2019, doi: https://doi.org/10.1016/j.cej.2019.121950 (IF 16.74)
12. Kumar N, Sinha S, Mehrotra T, Singh R, Tandon S,Thakur IS Biodecolorization of azo dye Acid Black 24 by Bacillus pseudomycoides: Process optimization using Box Behnken design model and toxicity assessment. Biores. Technol. Rep.2019 , 8, 100311
13. Jyoti S, Tandon S. Disruption of mitochondrial membrane potential coupled with alterations in cardiac biomarker expression as early cardiotoxic signatures in human ES cell-derived cardiac cells. Hum Exp Toxicol. 2019 Jun 10:960327119855132 (IF 3.24)
14. Srivastav R, Sharma R, Tandon S, Tandon C.Role of DHH superfamily proteins in nucleic acids metabolism and stress tolerance in prokaryotes and eukaryotes.Int J Biol Macromol. 2019 Apr 15;127:66-75 (IF 6.95)
15. 29.Basu N, Tandon S;Protocol standardization of homeopathic medicines' preparation and dosing for experimental model systems in vitro.Homeopathy. 2024 May 13. doi: 10.1055/s-0044-1786513

Project details

1. Principal Investigator
   

   In Vitro Approaches to Investigate the Efficacy and Mechanism of Action of Homeopathic Medicines Against Hormone Dependent and Independent Breast and Prostate Cancer

   2017-2019

   Agency-CCRH

   Amount -30lakhs

2. Principal Investigator To study the impact of Homeopathic Medicines on key genes and proteins controlling cell proliferation and cell death in Hormone Dependent and Independent Breast and Prostate Cancer
   

   2019-2022

   Agency-CCRH

   Amount -54lakhs

3. Application of Integrated Personal Omics Profile in the Treatment of
   

   Urolithiasis Using Homeopathic Approaches

   2024-2027

   Agency-CCRH

   Amount - 99 lakhs

1. c) Details of Commercialization / Technology transfer, if any.Not Applicable
2. d) Patent / Copyright, if any: Not Applicable

Name of the Faculty member: Prof. Manoj Garg

1. b) Total Research Publications - last 5 years

1. Gala K, Jain M, Shah P, Pandey AK, Garg M, Khattar E. Role of p53 transcription factor in determining the efficacy of telomerase inhibitors in cancer treatment. Life Sciences 2024;10:339:122416. (IF:6.87)
2. Jaiswal SR, Agarwal M, Bhagawati G, Das BC, Baligar P, Garg M, Biswas S, Chakrabarti S. Long-Term Follow-Up of Abatacept, Post-Transplantation Cyclophosphamide, and Sirolimus-Based Haploidentical Transplantation in Younger Patients with Nonmalignant Diseases. Transplant Cell Ther. 2024 Jun;30(6):605
3. Deswal B, Bagchi U, Santra MK, Garg M, Kapoor S. Inhibition of STAT3 by 2-Methoxyestradiol suppresses M2 polarization and protumoral functions of macrophages in breast cancer. BMC Cancer. 2024 Sep 10;24(1):1129.
4. Jaiswal SR, Agarwal M, Bhagawati G, Das BC, Baligar P, Garg M, Biswas S, Chakrabarti S. Long Term Follow-Up of Abatacept, Post-Transplantation Cyclophosphamide and Sirolimus (AbaCyS) based Haploidentical Transplantation in Younger Patients with Nonmalignant Diseases overlay panel. Transplantation and Cellular Therapy 2024; Mar 13:S2666-6367(24)00260-4.(IF: 3.2)
5. Kansara S, Sawant P, Kaur T, Garg M, Pandey AK. LncRNA-mediated orchestrations of alternative splicing in the landscape of breast cancer. Biochim Biophys Acta Gene Regul Mech. 2024 Jun;1867(2):195017.
6. Panwar V, Singh A, Bhatt M, Tonk RK, Azizov S, Raza AS, Sengupta S, Kumar D, Garg M*. Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease. Nature Signal Transduct Target Ther. 2023 Oct 2;8(1):375. (IF:40).
7. Kirtonia A, Pandey AK, Ramachandran B, Mishra DP, Dawson DW, Sethi G, Ganesan TS, Koeffler HP, Garg M*. Overexpression of laminin-5 gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascade. Cellular and Molecular Life Sciences 2022;79(7):362.(IF:9.27).
8. Kanojia D, Kirtonia A, Valli SNS, Jeevanandan SP, Shyamsunder P, Sampath SS, Dakle P, Mayakonda A, Kaur H, Jiang Y, Koeffler HP, Garg M*. Transcriptome analysis identifies novel lncRNA in liposarcoma that interacts with FOXM1 promoting liposarcoma proliferation. Pharmacological Research 2022;Sep 24;185:106462. (IF:10.33).
9. Kumar S, Ali I, Abbas F, Rana A, Pandey S, Garg M, Kumar D. In-silico design, pharmacophore-based screening, and molecular docking studies reveal that benzimidazole-1,2,3-triazole hybrids as novel EGFR inhibitors targeting lung cancer. J Biomol Struct Dyn. 2023 Aug 30:1-23. (IF: 4.1)
10. Kumar S, Ali I, Abbas F, Khan N, Gupta MK, Garg M, Kumar S, Kumar D. In-silico identification of small molecule benzofuran-1,2,3-triazole hybrids as potential inhibitors targeting EGFR in lung cancer via ligand-based pharmacophore modeling and molecular docking studies. In Silico Pharmacol. 2023 Aug 9;11(1):20.
11. Sharma D, Singh M, Joshi J, Garg M, Chaudhary V, Blankenberg D, Chandna S, Kumar V, Rani R. Design and Synthesis of Thiazole Scaffold-Based Small Molecules as Anticancer Agents Targeting the Human Lactate Dehydrogenase A Enzyme. ACS Omega 2023;8(20):17552-17562.(IF:4.132).
12. Singh M, Sharma D, Garg M, Kumar A, Baliyan A, Rani R, Kumar V. Current understanding of biological interactions and processing of DNA origami nanostructures: Role of machine learning and implications in drug delivery. Biotechnol Adv. 2022 Dec;61:108052.(IF:17.68)
13. Basu N, Garg M, Tandon C, Das BC, Tandon S. Arsenicum album Induces Cell Cycle Arrest and Apoptosis, and Inhibits Epithelial-Mesenchymal Transition in Hormone-Dependent MCF7 Breast Cancer Cells. Homeopathy 2022; 8. doi: 10.1055/s-0042-1755364.
14. Das AK, Gogia A, Garg M, Elaiyaraja A, Arambam P, Mathur S, Rajendran RB, Deo SVS, Kumar L, Das BC, Janardhanan R. Urinary concentration of endocrine-disrupting phthalates and breast cancer risk in Indian women: A case-control study with a focus on mutations in phthalate-responsive genes. Cancer Epidemiology 2022; 79:102188. (IF:2.89).
15. Sidhanth C, Bindhya S, Krishnapriya S, Manasa P, Shabna A, Alifia J, Patole C, Kumar V, Garg M, Ganesan TS. Phosphoproteome of signaling by ErbB2 in ovarian cancer cells. Biochim Biophys Acta Proteins Proteom 2022;1870(4):140768.(IF: 4.125)
16. Pandya G, Kirtonia A, Singh A, Goel A, Mohan CD, Rangappa KS, Pandey AK, Kapoor S, Tandon S, Sethi G, Garg M*. A comprehensive review of the multifaceted role of the microbiota in human pancreatic carcinoma.Seminar in Cancer Biology 2021; 26:S1044-579X(21)00157-7. (IF: 17.012).
17. Arora L, Mohan CD, Yang MH, Rangappa S, Deivasigamani A, Kumar AP, Kunnumakkara AB, Garg M, Chinnathambi A, Alharbi SA, Alahmadi TA, Rangappa KS, Hui KM, Sethi G, Ahn KS. Tris(dibenzylideneacetone)dipalladium(0) (Tris DBA) Abrogates Tumor Progression in Hepatocellular Carcinoma and Multiple Myeloma Preclinical Models by Regulating the STAT3 Signaling Pathway. Cancers (Basel) 2021;13(21):5479. (IF: 6.57)
18. Bindhya S, Sidhanth C, Krishnapriya S, Garg M, Ganesan TS. Development and in vitro characterization of an induced pluripotent stem cell model of ovarian cancer. The International Journal of Biochemistry and Cell Biology 2021;138:106051.(IF: 5.65).
19. Pandya G, Kirtonia A, Sethi G, Pandey AK, Garg M*. The implication of long non-coding RNAs in the diagnosis, pathogenesis and drug resistance of pancreatic ductal adenocarcinoma and their possible therapeutic potential. BBA Reviews on Cancer 2020;1874(2): 188423. (IF: 11.41)
20. Lee JH, Mohan CD, Deivasigamani A, Jung YY, Rangappa S, Basappa S, Chinnathambi A, Alahmadi TA, Alharbi SA, Garg M, Lin ZX, Rangappa KS, Sethi G, Hui, KM, Ahn KS. Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma. Journal of Advanced Research 2020;13;26:83-94.(IF:12.82).
21. Chien W, Sudo M, Ding LW, Sun QY, Wuensche P, Lee KL, Hattori N, Garg M, Xu L, Zheng Y, Gery S, Wongphayak S, Yang H, Baoglu E, Shacham S, Kauffman M, Mori, Koeffler HP. Functional Genome-wide screening identifies targets and pathways sensitizing pancreatic cancer cells to dasatinib. Journal of Cancer 2018;9(24):4762-4773.(IF: 4.47).
22. Kanojia D, Garg M, Martinez J, M T A, Luty SB, Doan NB, Said JW, Forscher C, Tyner JW, Koeffler HP. Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets. Journal of Hematology and Oncology 2017;10(1):173.(IF: 23.17)
23. Garg M*, Kanojia D, Mayakonda A, Ganesan TS, Sadhanandhan B, Suresh S, S S, Nagare RP, Said JW, Doan NB, Ding LW, Baloglu E, Shacham S, Kauffman M, Koeffler HP . Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin. Scientific Reports 2017;7(1):9749. (IF: 4.99)
24. Garg M*, Kanojia D, Mayakonda A, Said JW, Doan NB, Chien W, Ganesan TS, Chuang LS, Venkatachalam N, Baloglu E, Shacham S, Kauffman M, Koeffler HP. Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma.Oncotarget 2017;8(5):7521-7532.(IF: 6.0)
25. Kirtonia A, Ashrafizadeh M, Zarrabi A, Hushmandi K, Zabolian A, Bejandi AK, Rani R, Pandey AK, Baligar P, Kumar V, Das BC, Garg M*. Long noncoding RNAs: A novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia. Journal Cellular Physiology 2022;237(1):450-465.(IF: 6.38)
26. Sharma A, Kansara S, Mahajan M, Yadav B, Garg M, Pandey AK. Long non-coding RNAs orchestrate various molecular and cellular processes by modulating epithelial-mesenchymal transition in head and neck squamous cell carcinoma.Biochim Biophys Acta Mol Basis Dis. 2021 Nov 1;1867(11):166240.(IF: 10.50).
27. Sneha S, Nagare RP, Siddhanth C, Krishnapriya S, Garg M, Ramachandran B, Murhekr K, Sundersingh S, Ganesan TS. The hedgehog pathway regulates cancer stem cells in serous adenocarcinoma of the ovary. Cellular Oncology 2020; 43(4):601-616.(IF: 7.05).
28. Yadav B, Pal S, Rubstov Y, Goel A, Garg M, Pavlyukov M, Pandey AK. LncRNAs associated with glioblastoma: From transcriptional noise to novel regulators with a promising role in therapeutics. Molecular Therapy Nucleic Acids 2021; Apr 2;24:728-742. (IF: 10.18).
29. Garg M*, Shanmugam MK, Bhardwaj V, Goel A, Gupta R, Sharma A, Baligar P, Kumar AP, Goh BC, Wang L, Sethi G. The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy. Medicinal Research Reviews 2020 Dec 1. doi: 10.1002/med.21761.(IF: 13.59).
30. Kirtonia A, Gala K, Fernandes SA, Pandya G, Pandey AK, Sethi G, Khattar E, Garg M*. Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics. Seminar in Cancer Biology 2020;5:S1044-579X(20)30094-8. (IF: 17.12)
31. Gupta B, Sadaria D, Warrier VU, Kirtonia A, Kant R, Awasthi A, Baligar P, Paul JK, Yuba E, Sethi G, Garg M*, Gupta RK. Plant lectins and their usage in preparing targeted nanovaccines for cancer immunotherapy. Seminar in Cancer Biology 2022 May;80:87-106.(IF: 17.12)
32. Kirtonia A, Sethi G, Garg M*. The multifaceted role of reactive oxygen species in tumorigenesis.Cellular and Molecular Life Sci. 2020; 77(22):4459-4483. (IF: 9.27).
33. Kirtonia A, Pandya G, Sethi G, Pandey AK, Das BC, Garg M*. A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia. Journal of Molecular Medicine (Berl) 2020; 98(8):1069-1091.(IF: 5.6)
34. Shermane Lim YW, Xiang X, Garg M, Le MT, Li-Ann Wong A, Wang L, Goh BC. The double-edged sword of H19 lncRNA: Insights into cancer therapy. Cancer Letters 2021; 500:253-262. (IF: 9.75)
35. Morgan D, Garg M, Tergaonkar V, Tan SY, Sethi G. Pharmacological significance of the non-canonical NF-κB pathway in tumorigenesis. Biochimica Biophysica Acta Review on Cancer 2020;1874(2):188449. (IF: 10.50).
36. Kansara S, Pandey V, Lobie PE, Sethi G, Garg M, Pandey AK. Mechanistic Involvement of Long Non-Coding RNAs in Oncotherapeutics Resistance in Triple-Negative Breast Cancer. Cells (MDPI) 2020; 9(6):E1511. (IF: 7.666).
37. Pal S, Garg M, Pandey AK. Deciphering the mounting complexity of the p53 regulated network in correlation to long non-coding RNAs (lncRNAs) in ovarian cancer. Cells 2020; 25;9(3):527. (IF: 7.666).
38. Bindhya S, Sidhanth C, Shabna A, Krishnapriya S, Garg M, Ganesan TS. Induced pluripotent stem cells: A new strategy to model human cancer. International Journal of Biochemistry & Cell Biology 2019; 14;107:62-68. (IF 5.652).

1. c) Funded research project of last 5 years with completion date - Govt. & Industry

2023-2026 Principal Investigator, Development of nanotherapeutic systems for siRNA/ASO based. inhibition of SNHG5 lncRNA in Pancreatic Ductal Adenocarcinoma from the SERB-Core Research Grant, Government of India. Rs. 44,00,000. Ongoing

2022-2025 Principal Investigator, Deciphering the oncogenic role of SOX21 Antisense RNA 1 lncRNA and its potential as a therapeutic target for pancreatic ductal adenocarcinoma From the Indian Council of Medical Research (ICMR), Government of India. Rs. 47,06,696. Ongoing

2023-2028 DST-Inspire Fellowship project of PhD student Miss Bhavana Singh "Role of Long non-coding RNA(s) in PDAC. 35 Lakks

2020-2024 CO-Principal Investigator, Development of 3D in vitro bio-printed liver disease models for anti-fibrotic drug screening from the Indian Council of Medical Research (ICMR), Government of India. Rs. 51,70,000. Ongoing

2023-2026 CO-Principal Investigator, Generation of Induced Pluripotent Stem Cells on 3D Printed Gelatin-based Scaffold for the Treatment of Alpha-1 Antitrypsin Deficiency from the Department of Biotechnology, New Delhi, India. Rs. 46,00,000. Ongoing

2017–2020 Principal Investigator, Characterization of basement membrane protein laminin-5 gamma-2 (LAMC2) expression and its role in the progression and metastasis of pancreatic ductal adenocarcinoma from the Science and Engineering Research Board, Government of India. Rs. 47,55,320. Completed.

2016–2022 Principal Investigator, Role of MLL2 and MLL3 in acute myeloid leukemia from Department of Biotechnology (DBT), Government of India. Rs. 1,20,00,000. Completed

2017–2020 CO-Principal Investigator, CD24 IgG-Fc fusion protein as a therapeutic approach for ovarian cancer from the Department of Biotechnology. Rs.80,00,000. Completed

2019–2022 CO-Principal Investigator, A translational approach to inhibit hepatoma cell stemness by altering survival signals to prevent recurrence of carcinogenesis from the Indian Council of Medical Research (ICMR), Government of India. Rs. 87,00,000. Completed

1. d) Details of Commercialization / Technology transfer, if any.Not Applicable
2. e) Patent / Copyright, if any: patent number 202411066470.

Name of the Faculty member: Prof. Prakash Baligar

1. b) Total Research Publications - last 5 years

Publications,

1	Nautiyal N, Maheshwari D, Kumar D, Rao EP, Tripathi DM, Kumar S, Diwakar S, Bhardwaj M, Mohanty S, Baligar P, Kumari A, Bihari C, Biswas S, Sarin SK and Kumar A (2024) Rejuvenating bone marrow hematopoietic reserve prevents regeneration failure and hepatic decompensation in animal model of cirrhosis. Front. Immunol. 2024, 15:1439510. doi: 10.3389/fimmu.2024.1439510. (IF 5.7)
2	Jaiswal SR, Agarwal M, Bhagawati G, Das BC, Baligar P, Garg M, Biswas S, Chakrabarti S. Long-Term Follow-Up of Abatacept, Post-Transplantation Cyclophosphamide, and Sirolimus-Based Haploidentical Transplantation in Younger Patients with Nonmalignant Diseases. Transplant Cell Ther. 2024 Jun;30(6):605.e1-605.e13. doi: 10.1016/j.jtct.2024.03.010. Epub 2024 Mar 13. PMID: 38490295.
3	Kshama Kumari, Preeti Rawat, Arka Sanyal, Vinit Kumar, Manoj Garg, Debrupa Lahiri, Sourabh Ghosh, Prakash Baligar*. Current landscape and opportunities in the development of bioengineered in-vitro vascularized liver tissue models. Bioprinting. Volume 41, September 2024, e00350. https://doi.org/10.1016/j.bprint.2024.e00350.
4	Jaiswal, Sarita Rani; Agarwal, Mahak; Bhagawati, Gitalid; Das, Bhudev Chandra; Baligar, Prakash; Garg, Manoj; Biswas, Subhrajitc; Chakrabarti, Suparno. Long-Term Follow-Up of Abatacept, Post-Transplantation Cyclophosphamide, and Sirolimus-Based Haploidentical Transplantation in Younger Patients with Nonmalignant Diseases (2024) Transplantation and Cellular Therapy. DOI 10.1016/j.jtct.2024.03.010 (IF 3.2).
5	Kumari K, Tandon S, Ghosh S, Baligar P*. Gelatin scaffold ameliorates proliferation & stem cell differentiation into the hepatic-like cell and supports liver regeneration in partial-hepatectomized mice model. Biomed Mater. 2023 Nov 1;18(6). doi: 10.1088/1748-605X/ad04fd. PMID: 37860885. (IF 4.10).
6	Khan S, Baligar P, Tandon C, Nayyar J, Tandon S. Molecular heterogeneity in prostate cancer and the role of targeted therapy. Life Sciences. 2023 Nov 16:122270. doi: 10.1016/j.lfs.2023.122270. Epub ahead of print. PMID: 37979833. (IF 6.1).
7	Samarth Kansara, Agrata Singh, Abhishesh Kumar Badal, Reshma Rani, Prakash Baligar, Manoj Garg, Amit Kumar Pandey, The emerging regulatory roles of non-coding RNAs associated with glucose metabolism in breast cancer, Seminars in Cancer Biology, Volume 95, 2023, Pages 1-12, ISSN1044-79X,https://doi.org/10.1016/j.semcancer.2023.06.007.https://www.sciencedirect.com/ science/article/pii/S1044579X23000986). (IF 15.7).
8	Equbal Z, Baligar PN, Srivastava M, Mukhopadhyay A. A Two-Stage Process for Differentiation of Wharton's Jelly-Derived Mesenchymal Stem Cells into Neuronal-like Cells. Stem Cells Int. 2021 May 28;2021:6631651. doi: 10.1155/2021/6631651. PMID: 34135973; PMCID: PMC8177978. (IF 5.44).
9	Kirtonia A, Ashrafizadeh M, Zarrabi A, Hushmandi K, Zabolian A, Bejandi AK, Rani R, Pandey AK, Baligar P, Kumar V, Das BC, Garg M. Long noncoding RNAs: A novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia. J Cell Physiol. 2021 Sep 27. doi: 10.1002/jcp.30590. Epub ahead of print. PMID: 34569616. (IF – 6.38).
10	Dhruv Kumar, Prakash Baligar, Rajpal Srivastav, Priyanka Narad, Chanderdeep Tandon, Simran Tandon. Toxicity Prediction: How stem cells have expanded the horizons Current Pharmaceutical Design (MDPI) doi: 10.2174/1381612826666201019104712. 2020 (IF 3.11).
11	Garg M, Shanmugam MK, Bhardwaj V, Goel A, Gupta R, Sharma A, Baligar P, Kumar AP, Goh BC, Wang L, Sethi G. The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy. Med Res Rev.2020 Dec 1. doi: 10.1002/med.21761. Epub ahead of print. PMID: 33289118. (IF 12.9).
12	Gupta B, Sadaria D, Warrier VU, Kirtonia A, Kant R, Awasthi A, Baligar P, Pal JK, Yuba E, Sethi G, Garg M, Gupta RK. Plant lectins and their usage in preparing targeted nanovaccines for cancer immunotherapy. Semin Cancer Biol. 2020 Feb 14:S1044-579X(20)30038-9. doi: 10.1016/j.semcancer.2020.02.005. Epub ahead of print. PMID: 32068087. (IF 15.7).

Research Projects (as a PI)

	Title of Project	Grant/Fellowship/Year	Amount	Funded by	Status
1.	“Ex vivo partial liver organ development by using stem cells and tissue engineering approaches” ECR/2016/001508/ES	Research Grant 2017 - 2022	47.67 Lakhs	SERB, Govt. of India.	Completed
2.	“Development of natural skin with hair follicles and skin integumentary organs using 3D printed gelatin-elastin composite and iPSCs” ICMR-2021-12899 (ITR)	Research Grant 2022 - 2025	46.09 Lakhs	ICMR, Govt. of India.	Ongoing
3.	Generation of Induced Pluripotent Stem Cells on 3D Printed Gelatin-based Scaffold for the Treatment of Alpha-1 Antitrypsin Deficiency BT/PR39840/MED/31/461/2022	Research Grant 2022 - 2025	55.8 Lakhs	DBT, Govt. of India.	Approved
4	EMBO Grant Co-organizer for EMBO Lecture Course on “Tumour metabolism: Current Understanding and opportunities for novel drug discovery”	EMBO	Euro 45000		Marrch 28th-31st 2023

1. c) Details of Commercialization / Technology transfer, if any- NIL
2. d) Patent / Copyright, if any- NIL
3. e) MoUs, if any- 1 with IFS (Indian Fertility Society)

Name of the Faculty member: Prof. Pallavi Agarwal

1. b) Total Research Publications - last 5 years (9 Publications, 2 Book chapters)

• Hitesh K Sharma, Amarnath Karna, Sajendra K Verma, Puneet Gupta, Dheeraj Nagpal, Anoop Kumar, Deepti Pandita, Monalisa Mukherjee, Virinder S Parmar, Pallavi Agarwal, Viney Lather (2024) Exploring the Synergistic Effect of Thymol with Oxacillin against Methicillin Resistant Staphylococcus aureus. Indian Journal of Microbiology. (doi:10.1007/s12088-024-01311-9) (IF: 3)

• Nath S and Agarwal P (2023), Editorial: Genetic regulation of mitosis and ploidy in cancer. Frontiers in Genetics. 14:1264772. (doi: 10.3389/fgene.2023.1264772) (IF: 4.77)) (*corresponding Author)

• Amiya Das, Anita Prajapati, Amarnath Karna, Hitesh Kumar Sharma, Sheetal Uppal, Viney Lather*, Deepti Pandita*, Pallavi Agarwal* (2023) Structure-based virtual screening of chemical libraries as potential MELK inhibitors and their therapeutic evaluation against breast cancer; Chemico-Biological Interactions 376, 110443 (IF:5.2))(*corresponding Author)

• Amiya Das, Hitesh Kumar Sharma, Viney Lather*, Deepti Pandita* and Pallavi Agarwal* (2023) Structure-based virtual screening and therapeutic evaluation of small molecules as CDC20 inhibitors in breast cancer: A drug repurposing approach 3 Biotech 13, 141 (IF: 2.9))(*corresponding Author)

• Amiya Das, Pallavi Agarwal, Gaurav Kumar Jain, Geeta Aggarwal, Deepti Pandita, Viney Lather (2022) Repurposing drugs as novel triple negative breast cancer therapeutics. Anti-Cancer Agents in Medicinal Chemistry 22; 3:515-550. (IF – 2.55)

• Topno R^$; Singh I^$; Kumar M*; Agarwal P* (2021) Integrated bioinformatic analysis identifies UBE2Q1 as a potential prognostic marker for high grade serous ovarian cancer; BMC Cancer Mar 4;21(1):220. (IF- 4.4) (*corresponding Author)

• Topno R^$; Nazam N^$; Kumari P, Kumar M*; Agarwal P* (2021); Integrative genome wide analysis of protein tyrosine phosphatases identifies CDC25C as prognostic and predictive marker for chemoresistance in breast cancer; Cancer Biomarkers 2021;32(4):491-504 (IF- 4.38) (*corresponding Author)

• Amiya Das, Deepti Pandita, Gaurav Kumar Jain, Pallavi Agarwal, Ajmer Singh Grewal, Roop Krishen Khar, Viney Lather (2021) Role of phytoconstituents in the management of COVID19. Chemico-Biological Interactions 341, 109449 (IF – 5.2)

• Mehreen Aftab, Satish Poojari, Vaishnavi Seshan, Sachin Kumar, Pallavi Agarwal, Simran Tandon, Vijay Zutshi, Bhudev Das (2021) Urine miRNA signature as a potential non-invasive diagnostic and prognostic biomarker in cervical cancer Scientific Reports May 14;11: 10323 (IF – 5.1)

Book Chapter

• Nazia Nazam, Ravi Teja Chatava, Pallavi Agarwal (2019) ‘Lactate dehydrogenase: The role in the Warburg effect and Cancer’ ( Lactate dehydrogenase (LDH) Biochemistry, Function and Clinical Significance) USA: Nova Science Publishers Inc. New York, 11 (*corresponding Author)
• Sonia Kapoor, Pallavi Agarwal, Amiya Das, Simran Tandon (2023) ‘Targeting the tumor microenvironment: Changing the landscape of cancer’ (Molecular Biomarker) Cambridge Scholars Publishing Limited (Proof Read Submitted)

1. c) Funded research project of last 5 years with completion date - Govt. & Industry

6 completed projects, 3 ongoing

Sl. No.	Title of the project	Sanction No. /duration	Total Cost (in Rs.)	Agency	Present status	Role (PI/CI)
1.	Development of Urine based mRNA-surveillance biomarker panel for monitoring recurrence in high grade bladder cancer patients	2021-12632 (March 2023 – 2026)	63,00,000	ICMR	Ongoing	PI
2.	Unravelling role of epigenetic modulators in radiation-induced DNA Damage Response (DDR) and radioresistance pathways	58/14/16/2021-BRNS (Nov 2021 – Nov 2024)	39,06,600	BRNS-DAE	Ongoing	PI
3.	Unravelling oncogenic role of sirtuin 6 in Ovarian cancer (SRF: Mr. Amarnath Karna)	(Awarded) 2020-7968 (2022 – 2025)	12,60,000	ICMR-SRF	On-going	SRF mentor

6b. Completed Research Projects

Sl. No.	Title of the project	Sanction No. /duration	Cost (in Rs.)	Agency	Present status	Role
1.	Identifying new cancer drivers and exploring their transcriptional regulation in ovarian cancers to develop new therapeutic approaches	BT/RLF/Re-entry/16/2016 (2018 – 2023)	1,03,60,000	DBT-Ramalingaswami Fellowship	Completed	PI
2.	Analysis of key gene mutations and miRNAs and their interaction with Fos-related antigen 1/2 (Fra-1/2) to identify therapeutic target(s) in triple negative breast cancer stem cells	2019-0879 (2019 – 2022) (PI: Prof. Das)	79,02,000	ICMR Adhoc	Completed	Co-investigator
3.	Deciphering therapeutic potential of an epigenetic target in ovarian tumorigenesis and drug resistance (PDF: Dr. Nazia Nazam)	(Awarded) 2020 – 2023	17,52,000	ICMR-RA	Completed	RA mentor
4.	Dissecting epigenomics of high-grade serous ovarian cancers to identify new therapeutic targets	ECR/2017/000857 (2018 – 2021)	47,62,560	DST-SERB ECRA	Completed	PI
5.	Understanding epigenetic regulation of chemoresistance pathways in ovarian cancers to develop new therapeutic approaches	BT/PR18554/BIC/101/259/2016 2017 - 2020	38,26,628	DBT-Biocare Extramural Grant	Completed	PI
6.	Study of oncogenic drivers and their transcriptional regulation in ovarian cancers (Student PI – Ibha Singh)	SR/WOS-A/LS-471/2018 (2019 – 2022)	23,49,560	DST-WOSA	Completed	Mentor

1. d) Details of Commercialization / Technology transfer, if any None
2. e) Patent / Copyright, if any (01)

Title of the Invention: “An Anti-Cancer Potential Of 2-(1H-IMIDAZOL-5-YL) Phenol Derivatives and Method Thereof” Application No. E-2/1376/2023/DEL dated 15 September 2022

Name of the Faculty member: Prof. Vinit Kumar

1. b) Total Research Publications - last 5 years

Publications: Thematic Issue'Tumor Glycolysis' R Rani, V Kumar Seminars in cancer biology, S1044-579X (24) 00053-1	2024
Current Landscape and Opportunities in the development of Bioengineered In-Vitro Vascularized Liver Tissue Models K Kumari, A Sanyal, P Rawat, V Kumar, M Garg, D Lahiri, S Ghosh, ... Bioprinting, e00350	2024
GLUT and HK: two primary and essential key players in Tumor glycolysis D Yadav, A Yadav, S Bhattacharya, A Dagar, V Kumar, R Rani Seminars in Cancer Biology	4	2024
Synthesis and growth mechanism of vertically aligned graphene sheets with precise control over the number of layers for lithium–oxygen batteries A Kumar, A Dager, M Kumar, S Shamra, A Baliyan, V Kumar Journal of Materials Chemistry A	2024
A bis-quinoline ruthenium (ii) arene complex with submicromolar cytotoxicity in castration-resistant prostate cancer cells TA Khan, K Bhar, R Samanta, S Bhatt, M Singh, R Rani, V Kumar, ... Chemical Communications 60 (12), 1579-1582	1	2024
The metabolic crosstalk between PIN1 and the tumour microenvironment I Caligiuri, C Vincenzo, T Asano, V Kumar, F Rizzolio Seminars in Cancer Biology 91, 143-157	5	2023
Design and synthesis of thiazole scaffold-based small molecules as anticancer agents targeting the human lactate dehydrogenase A enzyme D Sharma, M Singh, J Joshi, M Garg, V Chaudhary, D Blankenberg, ... ACS omega 8 (20), 17552-17562	8	2023
Targeting monocarboxylate transporters (MCTs) in cancer: how close are we to the clinics? M Singh, J Afonso, D Sharma, R Gupta, V Kumar, R Rani, F Baltazar, ... Seminars in Cancer Biology 90, 1-14	40	2023
Targeting virus-induced reprogrammed cell metabolism via glycolytic inhibitors: An effective therapeutic approach against SARS-CoV-2 D Sharma, M Singh, R Gupta, M Garg, A Altieri, A Kurkin, V Kumar, R Rani Mini Reviews in Medicinal Chemistry 23 (2), 120-130	2	2023
Discovery of a potent Guanidine derivative that selectively binds and stabilizes the human BCL-2 G-quadruplex DNA and downregulates the transcription N Pandya, R Rani, V Kumar, A Kumar Gene 851, 146975	6	2023
G-quadruplex-mediated specific recognition, stabilization and transcriptional repression of bcl-2 by small molecule N Pandya, M Singh, R Rani, V Kumar, A Kumar Archives of Biochemistry and Biophysics 734, 109483	6	2023
Current understanding of biological interactions and processing of dna origami nanostructures: role of machine learning and implications in drug delivery M Singh, D Sharma, M Garg, A Kumar, A Baliyan, R Rani, V Kumar Biotechnology Advances 61, 108052	16	2022
Intervention on lactate in cancer: A promising approach for the development of cancer therapeutics D Sharma, M Singh, R Gupta, V Kumar, V Kumar, R Rani Advances in Cancer Biology-Metastasis 5, 100058	12	2022
BCL2 G quadruplex-binding small molecules: Current status and prospects for the development of next-generation anticancer therapeutics M Singh, R Gupta, L Comez, A Paciaroni, R Rani, V Kumar Drug Discovery Today 27 (9), 2551-2561	9	2022
Significant structural change in human c-Myc promoter G-quadruplex upon peptide binding in potassium N Kundu, T Sharma, S Kaur, M Singh, V Kumar, U Sharma, A Jain, ... RSC advances 12 (13), 7594-7604	11	2022
Long noncoding RNAs: a novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia A Kirtonia, M Ashrafizadeh, A Zarrabi, K Hushmandi, A Zabolian, ... Journal of cellular physiology 237 (1), 450-465	39	2022
In silico approach in drug design and drug discovery: an update N Jabalia, A Kumar, V Kumar, R Rani Innovations and Implementations of Computer Aided Drug Discovery Strategies …	16	2021
Selective inhibitors of human lactate dehydrogenase A to fight against metabolic cancer: a patent landscape V Kumar, R Rani Pharmaceutical Patent Analyst 9 (6), 155-157	8	2020
An effective multi-stage liposomal DNA origami nanosystem for in vivo cancer therapy S Palazzolo, M Hadla, C Russo Spena, I Caligiuri, R Rotondo, M Adeel, ... Cancers 11 (12), 1997	51	2019
Proof-of-concept multistage biomimetic liposomal DNA origami nanosystem for the remote loading of doxorubicin S Palazzolo, M Hadla, CR Spena, S Bayda, V Kumar, F Lo Re, M Adeel, ... ACS medicinal chemistry letters 10 (4), 517-521	52	2019
Microscopy A Baliyan, H Imai, V Kumar Data Processing Handbook for Complex Biological Data Sources, 97-117	4	2019
Lactate dehydrogenase enzyme: An old enzyme but new viable target offers new hope in cancer therapeutics V Kumar, R Rani LACTATE DEHYDROGENASE (LDH), 1	4	2019
Fourier transform infrared spectroscopy: Data interpretation and applications in structure elucidation and analysis of small molecules and nanostructures A Kumar, M Khandelwal, SK Gupta, V Kumar, R Rani Data processing handbook for complex biological data sources, 77-96	34	2019

Grants:

National

1. Title: Engineering DNA Origami-Based Nanodevice for Bio-applications and Multiplex Analysis,

SERB, 39 Lakh, 2018-2021 (PI)

1. Synthesis and Development of Deep Red/NIR Fluorescent Carbon Nanoparticles for Targeted Tumor Imaging, UPCST, 14 lakh, 2021-2024 (PI) (ongoing)
2. Title: Development of natural skin with hair follicles and skin integumentary organs using 3D printed gelatin-elastin composite and iPSCs, (2022-2025) CO-PI (ongoing)

International

1. Title: Structural analysis and unfolding dynamics of cMYC G-quadruplex upon Ligand binding using high filed NMR for next-generation anticancer therapeutics, European Commission, PI (2022-2024)
2. Title: Tumor Metabolism: Current Understandings and Opportunities for Novel Drug Discovery, EMBO, 45 lakh (2023)

1. Title: Tumor Metabolism: Current Understandings and Opportunities for Novel Drug Discovery, DBT Welcome Trust India Alliance 5.5 lakh (2023)
2. Identification of key genetic/epigenetic marker(s) in cervical carcinogenesis and development of corresponding molecular therapeutics for precision medicine of cervical cancer” DST BRICS (CO-PI) (2018-2021)

Patients: 5

Copyright: 1

Name of the Faculty member: Prof. Kajal Kanchan

1. b) Total Research Publications - last 5 years

1. Hritika Verma, Aditi Chauhan, Awanish Kumar, Manoj Kumar, Kajal Kanchan(2024), Synchronization of Mycobacterium life cycle: A possible novel mechanism of antimycobacterial drug resistance evolution and its manipulation. Life Science Journal 346, 122632. [IF 6.78]
2. Aditi Chauhan, Manoj Kumar, Awanish Kumar, and Kajal Kanchan* (2021) Comprehensive review on mechanism of action, resistance and evolution of antimycobacterial drugs. Life Science Journal 271, 119301 . [IF 6.78]
3. Manoj Kumar*, Komal Sharma*, Akhilesh K. Yadav*, Kajal Kanchan*, Madhu Baghel, Suneel Kateriya and Girdhar K. Pandey (2020) Genome-wide identification and biochemical characterization of calcineurin B-like calcium sensor proteins in Chlamydomonas reinhardtii. Biochemical Journal 477, 1879–1892. (*equal Contribution)[IF: 4.09]
4. Book chapter: Lactate Dehydrogenase, its isoforms and catalytic function, Aditi Dhawan and Kajal Kanchan, 2019, Nova publishers, ISBN 978-1-53615-103-9.

c) Funded research project of last 5 years with completion date - Govt.

& Industry:

1. ICMR funded project titled “Identifying novel transcriptional inhibitors for therapeutic targeting of M. tuberculosis SigE”. (Funds INR 80 Lakhs as PI) 2023-26 Ongoing
2. DST SERB funded project entitled “Genome-wide Identification of Tetratricopeptide Repeats (TPR) protein family from tuberculosis and their functional characterizationin virulence”. ( Funds INR 30.4 Lakhs as PI) 2022-2024, date of completion: 26^th January 2024
3. Ramalingaswami grant, DBT; Title: “Temperature sensing mechanism in tuberculosisand its role in pathogenesis”. (Funds INR 97.8 Lakhs, as PI) 2016-2020, date of completion: 30^th December 2020
4. ICMR funded project entitled “Elucidation of molecular mechanism and function of mycobacterial SigE in temperature perception, response and pathogenesis” (Funds INR – 50 Lakhs as PI) 2019-23, date of completion: 23rd March 2023
5. Consultancy project on “ Evaluation and validation of antimicrobial activity of nanoparticle containing fabrics and its technical testing, from Vviman Medical Textiles, a sister company of Suvi Exports. ( Funds 1.18 Lakhs), 2022-23, date of completion: 20th December 2023
6. Study of in-depth genetic heterogeneity with respect to resistome and compensatory adaption of MDR Mtb clinical strains inside BM- Mesenchymal stem cells circulating in the North East Region” ( Funds INR- 3.2 Corer as Co-PI) 2019-22, 30^thDecember 2022

d) Details of Commercialization / Technology transfer, if any: None

e) Patent / Copyright, if any: None

Name of the Faculty member: Dr. Sonia Kapoor

1. b) Total Research Publications - last 5 years

1. Deswal B, Bagchi U, Santra MK, Garg M, Kapoor S. Inhibition of STAT3 by 2-Methoxyestradiol suppresses M2 polarization and protumoral functions of macrophages in breast cancer. BMC cancer 24. 2024, 1129
2. Deswal B, Bagchi U, Kapoor S*. The immune-microenvironment confers chemoresistance in breast cancer through activation of VEGFR2/STAT3/BIRC5 signaling, 20, 100636, 2023. https://doi.org/10.1016/j.iotech.2023.100636
3. Deswal B, Bagchi U, Kapoor S*. Curcumin Suppresses M2 Macrophage-derived Paclitaxel Chemoresistance through Inhibition of PI3k-AKT/STAT3 Signaling. Anticancer Agents Med Chem. 2023 Nov 8. doi: 10.2174/0118715206275259231105184959.
4. Pandya G, Kirtonia A, Singh A, Goel A, Mohan CD, Rangappa KS, Pandey AK, Kapoor S, et al., comprehensive review of the multifaceted role of the microbiota in human pancreatic carcinoma. 2021 Semin Cancer Biol.:S1044-579X(21)00157-7
5. Deswal B, Kapoor S, Roy A. Targeting Tumor Microenvironment Through Nanotheranostics. In Nanomedicine for Cancer Diagnosis and Therapy ISBN 978-981-15-7564-8, © 2021 Springer.
6. Nadella V, Garg M, Kapoor S, Barwal TS, Jain A, Prakash H. Emerging neo adjuvants for harnessing therapeutic potential of M1 tumor associated macrophages (TAM) against solid tumors: Enusage of plasticity. Ann Transl Med June, 2021; 8(16):1029| http://dx.doi.org/10.21037/atm-20-695
7. Khan R, Chatterjee A, Ghosh H, Kapoor S*, Ray S (*Corresponding author). Phytochemicals as Anticancer Drugs: Targeting the Microtubular Network of Cancer Cells, in Phytochemistry: An in-silico and in-vitro Update. Springer Nature Singapore Pte Ltd. 2019 S. Kumar, C. Egbuna (eds.)
8. Chatterjee A, Rajarshi K, Ghosh H, Khan R, Kapoor S*, Ray S (*Corresponding author). An intimate alliance of DNA-damage response network with cell-cycle checkpoints amid events of uncontrolled cellular proliferation- a mini review. Endocrine, Metabolic & Immune Disorders-Drug Targets. 2020; doi: 10.2174/1871530320999200918143856
9. Kumar D, Walia NS, Kapoor S, Tandon S. Antibody-Targeted Nanoparticles for Cancer Treatment in NanoBioMedicine Springer Nature Singapore Pte Ltd. 2020; 35-65
10. Wasson M, Kapoor S, Garg M, Singh S, Prakash H. Macrophage Polarization is Decisive for Chronic Bacterial Infection induced Carcinogenesis In book: Macrophage at the Crossroads of Innate and Adaptive Immunity, 2019
11. Jain A, Singh SK, Arya SK, Kundu SC, Kapoor S*. Protein Nanoparticles: Promising Platforms for Drug Delivery Applications. ACS Biomater. Sci. Eng.2019, 4,12,3939-3961 ( *Corresponding author, Impact Factor: 5.4)
12. Kapoor S, Srivastava S, Panda D. Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Sci Rep. 2019; Nature Publishing group; 8:12363. (Impact Factor: 4.6)

1. c) Funded research project of last 5 years with completion date - Govt. & Industry:

	Title of the Project	Amount	Funding Agency
2023-2026	Role of HDAC6 in regulating plasticity and function of M2 Tumor-associated macrophages: A Potential therapeutic approach to modulate chemoresistance in breast cancer (ongoing, PI)	51 Lakhs	CRG DST, SERB
2023-2026	Investigating the role of p53 amyloid in the tumor associated macrophage polarization and tumor microenvironment of colorectal carcinoma (ongoing, Co-PI)	79.5 Lakhs	CRG DST, SERB
2018- 2022	Unveiling the Role of HDAC6: A Multipronged Approach to Restrict Breast Cancer Metastasis (Completed, PI)	33.32 Lakhs	DBT, BioCARE Award
2017- 2020	Probing Microtubule Remodeling in Tumor Associated Macrophages and its implication for Microtubule-targeted Chemotherapy (Completed, PI)	43.48 Lakhs	DST, Early Career Research Award
2016- 2018	Silk fibroin-based hydrogels for viscosupplementation and controlled drug delivery in Osteoarthritis (Completed, PI)	6 Lakhs	UGC, India (March 2016-March 2018)

1. d) Details of Commercialization / Technology transfer, if any: None
2. e) Patent / Copyright, if any: None

Name of the Faculty member: Dr. Subrata K. Pore

1. b) Total Research Publications - last 5 years

1. Anjali Singh, Subrata K Pore, Jayanta Bhattacharyyaa. Encapsulation of Telmisartan inside insulinoma cell-derived extracellular vesicle outperformed biomimetic nanovesicles in modulating pancreatic inflammatory microenvironment. J Mater Chem B. 2024 doi: 10.1039/d4tb00808a (Impact factor: 6.1)
2. Mattoo S, Gupta A, Chauhan M, Agrawal A, Subrata K Pore*. Prospects and challenges of noncoding-RNA-mediated inhibition of heat shock protein 90 for cancer therapy. Biochim Biophys Acta Gene Regul Mech 2024 1867(1):195006 (Impact factor: 4.7)
3. Hahm ER, Kim SH, Subrata K Pore, Mathan S, Singh RP, and Singh SV. Mechanisms of synergistic inhibitory effect of benzyl isothiocyanate and zoledronic acid combination on breast cancer induction of osteoclast differentiation. Molecular Carcinogenesis2024 63(2):301-313 (Impact factor: 5.1)
4. Subrata K Pore, Samanta SK, Gogoi B and Hahm ER. Editorial: Phytochemicals in cancer prevention and therapeutics: Current advancement and future perspective. Frontiers in Pharmacology 2023 14, doi.org/10.3389/fphar.2023.1156197 (Impact factor: 5.99)
5. Roy SM, Barman S, Basu A, Ghatak T, Subrata K Pore, Ghosh SK, Mukherjee R, Maity AR. Amine as a bottom-line functionality on DDS surface for efficient endosomal escape and further subcellular targets. Journal of Drug Delivery Science and Technology2022 71: 103303 (Impact factor: 5.0)
6. Subrata K Pore*, Hahm ER. Phytochemicals in Breast Cancer-Induced Osteoclastogenesis and Bone Resorption: Mechanism and Future PerspectiveCurrent Pharmacology Reports 2022 8:130-148 (Impact factor: 1.5)
7. Mukherjee S, Pramanik A, Subrata K Pore. Editorial: Immunomodulatory Nanomaterials in Cancer Theranostics. Frontiers in Chemistry 2021 13(9):691267 (Impact factor: 3.994)
8. Subrata K Pore, Hahm ER, Kim S, Singh KB, Nyiranshuti L, Latoche JD, Anderson CJ, Adamik J, Galson DL, Weiss KR, Watters RJ, Lee B, Kumta PN, and Singh SV. A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption. Molecular Cancer Therapeutics2020, 19(2), 420-431 (Impact factor: 5.7)
9. Subrata K Pore*, Ganguly A, Sau S, Godeshala S, Kanugula AK, Ummanni R, Kotamraju S, and Banerjee R*. N-end rule pathway inhibitor sensitizes cancer cells to antineoplastic agents by regulating XIAP and RAD21 protein expression. J Cell Biochem2020, 121(1), 804-815 *corresponding author (Impact factor: 4.0)

1. c) Funded research project of last 5 years with completion date - Govt. & Industry

1. PI: (Jul 2019 – Jun 2024) Development of Hsp90-regulating microRNA-Based Therapeutics in Breast Cancer. Rs. 113.60 lakhs. DBT
2. Co-PI: (Oct 2023 – Sept 2026) Mineralocorticoid receptor targeted dendritic cell-derived exosomes for anticancer therapy. Rs. 26 lakhs. SERB-SURE
3. Co-PI: (Dec 2023 – Nov 2026) Calcium-permeable ion channels as therapeutic targets to manage neuropathic pain. Rs. 43.25 lakhs. DBT-multi-institutional
4. Co-PI: (2024 – 2027) Development and biological evaluation of the anti-cancer potential of glucocorticoid receptor-targeted exosomal formulation. Rs. 30 lakhs, CSIR-ASPIRE

1. Details of Commercialization / Technology transfer, if any: None
2. e) Patent / Copyright, if any:

1. Shria Mattoo, Zafar Iqbal, Saroj Ranjan De, Subrata Kumar Pore. (Provisional patent # 202411020916; Application Date: 20/03/24)

1. Zafar Iqbal, Saroj Ranjan De, Subrata Kumar Pore. (Patent # TEMP/E-1/15414/2024; Application Date: 30/06/2024)

1. f) MoUs - 1 with National Institute of Technology-Uttarakhand (NIT-Uttarakhand)

1. b) Total Research Publications - last 5 years

1. Yaduvanshi S and Kumar V# (2024). Fungal alkaloid malbrancheamide reorients the lipid binding domain of GRK5. J Biomol Struct Dyn (In press). (IF 4.15)
2. Diana Gomes, Yaduvanshi S, Kumar V#, Samuel Silvestre, Luís Passarinha, and Ângela Sousa (2023). Discovery of small molecules as HPV16/18 E6 protein potential inhibitors against cervical cancer. Accepted in IJBM.
3. Gomes D, Yaduvanshi S, Silvestre S, Duarte AP, Santos AO, Soares CP, Kumar V#, Passarinha L, and Sousa A (2022). Taxifolin and lucidin as potential E6 protein inhibitors: p53 function re-establishment and apoptosis induction in cervical cancer cells. Cancers 2022, 14(12), 2834. (IF 6.64)
4. Shivani Y, Ero R, Kumar V# (2021). The mechanism of complex formation between calmodulin and voltage gated calcium channels revealed by molecular dynamics. Plos One 16(10):e0258112. (IF 3.75)
5. Jaiswal G, Shivani Y, Kumar V# (2021). A Potential Peptide Inhibitor of SARS-CoV‑2 S and human ACE2 Complex. J Biomol Struct Dyn. 40(14):6671-6681 (IF 4.15).
6. Jaiswal G and Kumar V# (2020). In-silico design of a potential inhibitor of SARS-CoV-2 S protein. Plos One, 15(10): e0240004 (IF 3.75)
7. He Q, Toh JD, Ero R, Qiao Z, Kumar V, Serra A, Tan J, Sze SK, Gao YG (2020). The unusual di-domain structure of Dunaliella salina glycerol-3-phosphate dehydrogenase enables direct conversion of dihydroxyacetone phosphate to glycerol. Plant J. 102(1):153-164. (IF 7.1)
8. Ero R, Kumar V, Su WX, Gao YG (2019). Ribosome protection mechanism by ABC-F family of proteins. Protein Science (Cover Story), 28(4): 684-693. (IF 6.72)

Book chapters:

1. Authors: Chowdhury C, Garg M, Kumar V, Kumar V (2022).

Chapter: Structure of DNA.

Book Name: Manual of Assisted Reproductive Technologies and Laboratory Sciences

Publisher Name: Evangel Publishing

ISBN: 978-93-90616-09-1

1. Authors: Shivani Y, Kumar V (by invitation, submitted)

Chapter: Protein Bio-Interaction Analysis by Molecular Dynamics Simulation

Book Name: Advanced Methods in Structural Biology

Publisher: Springer Nature

ISBN: 978-1-0716-3146-1

1. c)Funded research project of last 5 years with completion date - Govt. & Industry

Title: “Voltage Gated Ca2+ Ion Channels as Therapeutic Drug Targets”

Amount (INR): 113.60 lakhs

Funding agency: Department of Biotechnology

Timeline: 2019-2024

d) Details of Commercialization / Technology transfer, if any: None

e) Patent / Copyright, if any: None

Name of the Faculty member: Dr. Adhiraj Roy

1. b) Total Research Publications - last 5 years

1. Protein kinase C iota promotes glycolysis via PI3K/AKT/mTOR signalling in high grade serous ovarian cancer. Tyagi K, Roy A^*, Mandal S, Molecular Biology Reports, 2024 Sep 14;51(1):983. doi: 10.1007/s11033-024-09918-3. (IF: 2.6)
2. Design, Synthesis, and Characterization of Polyoxotungstate-Decorated Ionic Liquid–Based Hybrid Material, [BmIm]₄[SiW₁₂O₄₀] toward Rapid Adsorption of Dye and Antibacterial Activities. Das S, Sen B, Sarkar S, Das I, Sepay N, Paul S, Mandal S, Roy A, Malecka M, Abbas JS, Gangavarapu RR, Vijaykumar B, Ali, IS, Inorganic Chemistry, September 2024. https://doi.org/10.1021/acs.inorgchem.4c01765. Online ahead of print (IF: 4.6)
3. Pharmacological inhibition of protein kinase D2/Aurora kinase A signalling axis suppresses G2/M cell cycle progression and proliferation of epithelial ovarian cancer cells. Sachdeva A, Roy A^*, Gupta MK, Mandal S, Pathology Research and Practice, June 12;260:155390. doi: 10.1016/j.prp.2024.155390. Online ahead of print (IF: 2.8)
4. Protein kinase D2-Aurora kinase A-ERK1/2 signalling axis drives neuroendocrine differentiation of epithelial ovarian cancer, Sachdeva A, Roy A^*, Mandal S, Molecular & Cellular Biochemistry, 1007/s11010-024-04986-2, April 2024, Online ahead of print (IF: 4.3)
5. A trinuclear Zn (II) schiff base dicyanamide complex attenuates bacterial biofilm formation by ROS generation and membrane damage and exhibits anticancer activity. Barua M, Bandyopadhyay S, Wasai A, Ghosh M, Roy I, Ghosh P, Koner S, Rizzoli C, Roy A^*, Saha S, Mandal S, Microbial Pathogenesis, https://doi.org/10.1016/j.micpath.2024.106548, January 2024, Online ahead of print (IF: 3.848)
6. Pharmacological inhibition of protein kinase D suppresses epithelial ovarian cancer via MAPK/ERK1/2/Runx2 signalling axis. Tyagi K, Roy A^*, Mandal S, Cellular Signalling, https://doi.org/10.1016/j.cellsig.2023.110849, August 2023, Online ahead of print (IF: 4.8)
7. A mononuclear N,N,N,O donor Schiff base Cu (II) complex inhibits bacterial biofilm formation and promotes apoptosis and cell cycle arrest in prostate cancer cells. Biswas S, Wasai A, Ghosh M, Rizzoli C, Roy A^*, Saha S, Mandal S, Journal of Inorganic Biochemistry, https://doi.org/10.1016/j.jinorgbio.2023.112314, July 2023, Online ahead of print (IF: 4.2)
8. Runt‑related transcription factors in human carcinogenesis: a friend or foe? Roy A^*, Chauhan S, Bhattacharya S, Jakhmola V, Tyagi K, Sachdeva A, Wasai A, Mandal S, Journal of Cancer Research and Clinical Oncology, https://doi.org/10.1007/s00432-023-04769-0, April 2023, Online ahead of print (IF: 4.322)
9. Protein kinase D2 and 3 promote prostate cancer cell bone metastasis by positively regulating Runx2 in a MEK/ERK1/2-dependent manner. Roy A, Prasad S, Chen Y, Chao Y, Liu Y, Zhao J, Wang QJ, Am J Pathol, 2023 Feb 3; S0002-9440(23)00036-6.doi: 10.1016/j.ajpath.2023.01.004. Online ahead of print (IF: 5.770)
10. Loss of Protein Kinase D2 Activity Protects Against Bleomycin-Induced Dermal Fibrosis in Mice. Chen L, Zhao J, Chao Y, Roy A, Guo W, Qian J, Xu W, Domsic RT, Lafyatis R, Lu B, Deng F, Wang QJ. Laboratory investigation. 2023 Feb;103(2):100018. doi: 10.1016/j.labinv.2022.100018. Epub 2023 Jan 10 (IF: 5.662)
11. Human microbial dysbiosis as driver of gynecological malignancies. Mandal S, Bandyopadhyay S, Tyagi K, Roy A^*, Biochimie. 2022 Feb 14;197:86-95. doi: 10.1016/j.biochi.2022.02.005. Online ahead of print (IF: 4.37. ^*Corresponding author)
12. Recent advances in understanding the molecular role of phosphoinositide-specific phospholipase C gamma 1 as an emerging onco-driver and novel therapeutic target in human carcinogenesis. Mandal S, Bandyopadhyay S, Tyagi K, Roy A^*, Biochim Biophys Acta Rev Cancer. 2021 Aug 21; 1876(2): https://doi.org/10.1016/j.bbcan.2021.188619. Online ahead of print. (IF: 11.414. ^*Corresponding author)
13. Recent advancements in therapeutic targeting of the Warburg effect in refractory ovarian cancer: A promise towards disease remission. Tyagi K, Mandal S, Roy A^*. Biochim Biophys Acta Rev Cancer. 2021 May 7;1876(1):188563. doi:10.1016/j.bbcan.2021.188563. Online ahead of print. (IF: 11.414. ^*Corresponding author)
14. Evaluating the current status of protein kinase C (PKC)-protein kinase D (PKD) signalling axis as a novel therapeutic target in ovarian cancer. Tyagi K, Roy A^*, Biochim Biophys Acta Rev Cancer, 2020 Dec 28;1875(1):188496. (IF: 414. ^*Corresponding author)
15. Oncogenic potential of nucleoporins in non-hematological cancers: recent update beyond chromosome translocation and gene fusion.Roy A^*, Narayan G. J Cancer Res Clin Oncol. 2019 Oct 25. 145(12), 2901-2910. Review. (IF: 553. ^*Corresponding author)
16. Protein Kinase D2 Modulates Cell Cycle by Stabilizing Aurora A Kinase at Centrosomes.Roy A, Veroli MV, Prasad S, Wang QJ. Mol Cancer Res. 2018 Nov;16(11):1785-1797. doi: 10.1158/1541-7786.MCR-18-0641. Epub 2018 Jul 17. (IF: 6.333)
17. Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway. Ye J, Das S, Roy A, Wei W, Huang H, Lorenz-Guertin JM, Xu Q, Jacob TC, Wang B, Sun D, Wang QJ. Mol Neurobiol. 2019 Mar;56(3):2123-2136. doi: 10.1007/s12035-018-1198-2. Epub 2018 Jul 11. (IF: 59)
18. c) Funded research project of last 5 years with completion date - Govt. & Industry:

• Elucidation of the role of autophagy in regulation of exosomal micro-RNA in triple negative breast cancer (PI), Indian Council of Medical Research (ICMR), Govt. of India (2021-2022), Rs. 947600 (Completion date: 28 ^th February 2022)
• Elucidation of the role of Protein kinase D (PKD) and PI3 kinase-Protein kinase C iota (PKCί) signaling axes in refractory ovarian cancer (PI), Department of Biotechnology (DBT), Govt. of India (2019-2024), Rs. 4000000 (Completion date: 28^th February 2024)

1. d) Details of Commercialization / Technology transfer, if any: None
2. e) Patent / Copyright, if any: 1

• “A nano-formulated Zinc (II) trinuclear complex for targeted prostate cancer therapy and method thereof”, Roy A, Nagpal K, Wasai A (Application No: TEMP/E-1/68049/2024-DEL), 2024

Name of the Faculty member: Dr. Jayasha Shandilya

1. b) Total Research Publications - last 5 years

1. Nayak TK, Vij R, Bruhova I, Shandilya J, Auerbach A. Efficiency measures the conversion of agonist binding energy into receptor conformational change. J. Gen. Physiol. 2019; 151:465-477.

Book chapters:

2. Khatoon N, Adusumilli S, Dey P, Sharma R, Kampani P, Shandilya J, Nayak TK. Protein engineering and design in ion channels and receptors. Methods Cell Biol.2022; 169:143-168.
3. Adusumilli S, Chauhan M, Mathe MM, Nayak TK, Shandilya J. Computational Biology for Stem Cell Research: Genomic and transcriptomic applications in neural stem cell therapeutics. Academic Press.
4. c) Funded research project of last 5 years with completion date - Govt. & Industry:

Ongoing Projects:

1. DBT- Ramalingaswami-Re-entry fellowship: Regulation of mitotic checkpoint function by NF-κB and p53 signaling network: implications in genomic instability and carcinogenesis. 113.6 Lakhs, 19/10/2020 To 19/10/2025
2. DBT Chronic/Lifestyle Disease Program: Calcium-permeable ion channels as therapeutic targets to manage neuropathic pain, 43.25 Lakhs, 28/12/2023 To 31/3/2026

1. d) Details of Commercialization / Technology transfer, if any: None
2. e) Patent / Copyright, if any: None

Name of the Faculty member: Dr. Shinjinee Dasgupta

1. b) Total Research Publications - last 5 years
2. 1. Gauri Tyagi and Shinjinee Sengupta* Unveiling the Multifaceted Potential of Amyloid Fibrils: From Pathogenic

Myths to Biotechnological Marvels, Biophysical Reviews, 2024 In Press (IF- 4.9)

2. 2. Shivi Chauhan#, Shivani Jaiswal#, Vibhuti Jakhmola#, Bhavana Singh, Sujata Bhattacharya, Manoj Garg+, Shinjinee Sengupta* Potential Role of p53 Deregulation in Modulating Immune Responses in Human Malignancies: A Paradigm to Develop Immunotherapy, Cancer Letters, 2024, Volume 588, 28 April 2024, 216766 (IF-9.7)* corresponding author
3. 3. Debalina Datta, Ambuja Navalkar, Arunima Sakunthala, Ajoy Paul, Komal Patel, Shalaka Masurkar, Laxmikant Gadhe, Shinjinee Sengupta, Manisha Poudyal, Jyoti Devi, Ajay Singh Sawner, Pradeep Kadu, Ranjit Shaw, Satyaprakash Pandey, Semanti Mukherjee, Nitisha Gahlot, Kundan Sengupta, Samir K Maji. Nucleo-cytoplasmic environment modulates spatio-temporal p53 phase separation. Preprint bioRxiv, 2023, doi: https://doi.org/10.1101/2023.10.16.562512 * Under revision in Science Advances (IF-13.7)
4. 4. Shinjinee Sengupta, Namrata Singh, Ajoy Paul, Debalina Datta, Debdeep Chatterjee, Semanti Mukherjee, Laxmikant Gadhe, Jyoti Devi, Yeshwant M, Mohit Kumar Jolly, and Samir Maji, p53 amyloid pathology is correlated with higher cancer grades irrespective of the mutant or wildtype forms, Journal of Cell Science, 2023, 136 (17): jcs261017. (IF- 5.2]
5. 5. Vivek Panwar, Aishwarya Singh, Manini Bhatt, Rajiv Tonk, Shavkatjon Azizov, Agha Saquib Raza, Shinjinee Sengupta*, Deepak Kumar* and Manoj Garg* Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease, Signal Transduction and Targeted Therapy. 2023, 2;8(1):37 [IF- 40]* corresponding author.
6. 6. Shaikh Maryam Ghufran, Prachi Sharma, Bornika Roy, Shivani Jaiswal, Mehreen Aftab, Shinjinee Sengupta, Sampa Ghose, Subhrajit Biswas* Transcriptome wide functional analysis of HBx expressing human hepatocytes stimulated with endothelial cell., Genomics, 2023, 115(4):110642 [IF-4.3].
7. 7. Sengupta S*, Ghufran SM, Khan A, Biswas S, Roychoudhury S, Transition of amyloid/mutant p53 from tumor suppressor to an oncogene and therapeutic approaches to ameliorate metastasis and cancer stemness. Cancer Cell International. 2022 Dec 26;22(1):416 [IF-6.4]*Corresponding author
8. 8. D. Chatterjee, R.S. Jacob, R. Kumar, N. Singh, P. Kadu, L. Gadhe, S. Sengupta, A. Navalkar, S. Mehra, N.N. Jha, A. Anoop, S. Kumar, D. G. Dastidar, P. S Singru, S. Senapati and S. K Maji, Co-aggregation and secondary nucleation in the life cycle of human prolactin/galanin functional amyloids, eLIFE, 2022 Mar 8;11:e73835. [IF-8.1]
9. 9. Shinjinee Sengupta, Deepti Sahasrabuddhe and Pramod P. Wangikar, Transporter Engineering for the development of Cyanobacteria as cell factories: A Text Analytics guided survey 2021, Biotechnology Advances, 107816. [IF-14.7]

10.VaibhavSrivastava,RuthAmanna,StephenJ.L.Rowden,ShinjineeSengupta,SwatiMadhu,ChristopherJ.Howe, Pramod P. Wangikar, Adaptive laboratory evolution of the fast-growing cyanobacterium Synechococcus elongatus PCC 11801 for improved solvent tolerance, 2021, Journal of Bioscience and Bioengineering, Volume 131, Issue 5, May 2021, Pages 491-500. [IF-2.24]

11.ShinjineeSengupta,DaminiJaiswal,AnneshaSengupta,ShikhaShah,ShrutiGadagkarandPramodP.Wangikar, Metabolic engineering of a fast-growing cyanobacterium Synechococcus elongatus PCC 11801 for photoautotrophic production of succinic acid, 2020, Biotechnology for Biofuels, 13, Article number 89. [IF-6.4]

12.DaminiJaiswal,AnneshaSengupta,ShinjineeSengupta,SwatiMadhu,HimadriPakrasi,andPramodWangikar,A Novel Cyanobacterium Synechococcus elongatus PCC 11802 has Distinct Genomic and Metabolomic Characteristics Compared to its Neighbor PCC 11801, 2019, Scientific Reports, 13, 10(1):191. [IF- 5.133]

13. 13. Arora, N., Jaiswal, D., Sengupta, S., Wangikar, P.P., 2020. Metabolic engineering of cyanobacteria for production of platform chemicals: A synthetic biology approach. In: Konur, O. (Ed.) The Handbook of Algal Science, Microbiology, Technology, and Medicine. Elsevier, Amsterdam, In Press.
14. 14. Deepti Sahasrabuddhe, Shinjinee Sengupta, Annesha Sengupta, Vivek Mishra and Pramod Wangikar, Cyanobacteria as renewable resource for biofuel production book chapter, Advanced biofuels technologies -Present status, challenges and future prospects, Ms Elsevier
15. 15. Cathepsins in cancer therapy and precision medicine, Namrata Singh, Aqsa Khan, Asma Mohin Rojewale and Shinjinee Sengupta* Handbook of proteases in cancer: Therapeutic aspects, 2023, CRC Press (Taylor and Francis). * corresponding author

c) Funded research project of last 5 years with completion date - Govt. & Industry:

1. DBT Wellcome Trust India Alliance (Completion date: 30th August 2024)

2. SERB CRG - ongoing (Completion date: 13th March 2027)

d) Details of Commercialization / Technology transfer, if any: None

e) Patent / Copyright, if any:

Patents

1. Patent granted on “Amyloid mediated cell line transformation”. Inventors: Samir K Maji, Saikat K Ghosh, Shinjinee Sengupta, Shimul Salot, Ambuja Navalkar, Subhadeep Das, Reeba S Jacob. Patent no. 361011.
2. Patent filled on “Method for photoautotrophic production of succinate using recombinant Synechococcus sp” Pramod Wangikar, Shinjinee Sengupta, Deepti Shrahastrabudhi, Swati Madhu and Damini Jaiswal. Patent application no. 202121022027.
3. Patent filled on “p53 amyloid-binding composition, method, and kit thereof”. Inventors: Samir K Maji, Ajoy Paul, Debalina Dutta, Shinjinee Sengupta Patent application no. 202421031922.

Name of the Faculty member: Dr. Yogita Adlakha

1. b) Total Research Publications - last 5 years

1. Yogita K Adlakha. Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. Cell Death and Discovery, 2023, Jul 3;9(1):221. (F. 7.11)
2. Ke Jiang*, Anupam K Mondal*, Yogita K Adlakha…….Robert S Balaban, Raul Covian, Anand Swaroop. Multiomics analyses reveal early metabolic imbalance and mitochondrial stress in neonatal photoreceptors leading to cell death in Pde6brd1/rd1 mouse model of retinal degeneration. Human Molecular Genetics, 2022 Jul 7;31(13):2137-2154. https://doi.org/10.1101/2021.10.10.463827. *equal co-first. (F. 6.15)
3. Asha S. Channakkar#, Tanya Singh, Bijay Pattnaik, Pankaj Seth, Yogita K. Adlakha#*. MiRNA-137-mediated modulation of mitochondrial dynamics regulates human neural stem cell fate. STEM CELLS. 2020, May;38(5):683-697. *Corresponding Author. # Equal Contribution as first author. (F. 6.3)

Our work made headlines, “NBRC scientists pave the way for a better understanding of Autism” in Hindu Business Line and Vigyan Prasar “India Science Wire” and BioTecNika. Selected for Cover Page of journal.

Department of Science and Technology highlighted our research on social media. Ministry of Science and Technology also released a report. India today and several other online news channels also published and highlighted our research.

4. Kaya KD, Chen HY, Brooks MJ,….. Adlakha YK, Welby E, Swaroop A. Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal. Molecular Vision, 2019; Nov 11;25:663-678. Preprint, bioRxiv 733071. (IF: 2.2).
5. Bhagat R, Prajapati B, Narwal S, Agnihotri N, Adlakha YK, Sen J and Seth P. Zika Virus E protein alters properties of human fetal neural stem cells by modulating microRNA circuitry. Cell Death and Differentiation, 2018, Nov;25(10): 1837-1854. (IF: 8.09).
6. Swaroop S, Mahadevan A, Shankar SK, **Adlakha YK, Basu A. HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway. Journal of Neuroinflammation, 2018 Jun 9;15(1):177. doi: 10.1186/s12974-018-1214-5. **Co-corresponding Author. (IF: 5.7).

1. c) Funded research project of last 5 years with completion date - Govt. & Industry

1. 2021-2024 Science and Engineering Research Board (SERB) Research Scientist grant,

Principal Investigator: Decrypting the molecular circuitry of human brain development: Expanding horizons of 3D human brain organoids for studying neurological disorders

Rs. 46,00,000. Completed.

2. 2022-2025 Women Excellence Award, Science and Engineering Research Board (SERB) grant, Principal Investigator: Exploring the molecular mechanisms mediated by vitamin D signaling in fetal neuronal development

18,00,000 Ongoing

1. d) Details of Commercialization / Technology transfer, if any: None
2. e) Patent / Copyright, if any: None

Name of the Faculty member: Dr. Priyanka Jain

1. b) Total Research Publications - last 5 years

• Singh N, Jain P, Ujinwal M and Langyan S (2022) Escalate protein plates from legumes for sustainable human nutrition. Front. Nutr. 9:977986. doi: 10.3389/fnut.2022.977986.
• Jain P, Singh A, Iquebal MA, Jaiswal S, Kumar S, Kumar D, Rai A. (2022) Genome-Wide Analysis and Evolutionary Perspective of the Cytokinin Dehydrogenase Gene Family in Wheat (Triticum aestivum L.). Front Genet. 19;13:931659.doi: 10.3389/fgene.2022.931659.
• Priya S., Tripathi G., Singh DB., Jain P., Kumar A. (2022) Machine learning approaches and their applications in drug discovery and design. Chemical Biology & Drug Design. https://doi.org/10.1111/cbdd.14057 .
• Jain P, Hussain S, Nishad J, Dubey H, Bisht DS, Sharma TR, Mondal TK. (2021) Identification and functional prediction of long non-coding RNAs of rice (Oryza sativa L.) at reproductive stage under salinity stress. Molecular Biology Reports. 10.1007/s11033-021-06246-8.
• Jain P, Dubey H, Singh PK, Solanke AU, Singh AK, Sharma TR. (2019) Deciphering signaling network in broad spectrum Near Isogenic Lines of rice resistant to Magnaporthe oryzae. Scientific Reports. 9:16939.
• Pandey V., Jain P.,Chatterjee S., Rani A., Tripathi A., Dubey P.K. (2024) Variants in exon 2 of MED12 gene causes uterine leiomyoma's through over-expression of MMP-9 of ECM pathway, Mutation Research 828,2024,111839.
• Singh, G., Ambreen, H., Jain, P., Chakraborty, A., Singh, B., Manivannan, A. et al. (2023) Comparative transcriptomic and metabolite profiling reveals genotype-specific responses to Fe starvation in chickpea. Physiologia Plantarum, 175( 2), e13897. 11)
• Panda AK, Rawal HC, Jain P, Mishra V, Nishad J, Chowrasia S, Sarkar AK, Sen P, Naik SK, Mondal TK. (2022) Identification and analysis of miRNAs-lncRNAs-mRNAs modules involved in stem-elongation of deepwater rice (Oryza sativa L.) Physiol Plant. Jul;174(4):e13736. doi: 10.1111/ppl.13736.
• Devanna, B. N., Jain, P., Solanke, A. U., Das, A., Thakur, S., Singh, P. K.,Sharma, T. R. et al. (2022) Understanding the Dynamics of Blast Resistance in Rice-Magnaporthe oryzae Interactions. Journal of Fungi, 8(6), 584.
• Kumar V, Jain P, Venkadesan S, Karkute SG, Bhati J, Abdin MZ, Sevanthi AM, Mishra DC, Chaturvedi KK, Rai A, Sharma TR, Solanke, AU. (2021) Understanding Rice-Magnaporthe Oryzae Interaction in Resistant and Susceptible Cultivars of Rice under Panicle Blast Infection Using a Time-Course Transcriptome Analysis. Genes-Basel.
• Limbalkar, O.M., Vasisth, P., Singh, G., Jain P.et al., et al. (2023) Dissection of QTLs conferring drought tolerance in B. carinata derived B. juncea introgression lines. BMC Plant Biol 23, 664.
• Jatan, R., Kamboj, R., Kumar, M. et al. Isolation and whole genome sequencing of Pseudomonas aeruginosa strain RK1 and its biocontrol potential against phytopathogens of rice. Biologia (2023). https://doi.org/10.1007/s11756-023-01406-6.
• Vasisth P, Singh N, Limbalkar OM, Sharma M, Dhanasekaran G, Meena ML, Jain P, Jaiswal S, Iquebal MA, Watts A, et al. 2023 Introgression of Heterotic Genomic Segments from Brassica carinata into Brassica juncea for Enhancing Productivity. Plants.; 12(8): 1677.https://doi.org/10.3390/plants12081677
• Tiwari IM, Vijayan J, Ray S, Jain P, Jatan R, Kumar N, Kumar M, Singh NK, Bisht DS. 92022) Selection of suitable internal control gene for assaying gene expression in rice through qRT-PCR during sheath blight infection. J Biotechnol. 2023 Jan 20;362:1-11. doi: 10.1016/j.jbiotec.2022.12.003.
• Devanna BN, Jaiswal R, Singh PK, Kapoor R, Jain P, Kumar G, Sharma Y, Sharma TR. (2021) Role of transporters in plant disease resistance. Physiologia Plantarum ppl.13377.
• Singh PK, Mahato AK, Jain P, Rathour R, Sharma V, Sharma TR. (2019) Comparative Genomics Reveals the High Copy Number Variation of a Retro Transposon in Different Magnaporthe Isolates. Frontiers in Microbiology 10:966.
• Kapoor R, Kumar G, Arya P, Jaswal R, Jain P, Singh K, Sharma TR. (2019) Genome-Wide Analysis and Expression Profiling of Rice Hybrid Proline-Rich Proteins in Response to Biotic and Abiotic Stresses, and Hormone Treatment. Plants (Basel). 8
• Dubey H, Kiran K, Jaswal R, Jain P, Kayastha AM, Bhardwaj SC, Mondal TK, Sharma TR. (2019) Discovery and profiling of small RNAs from Puccinia triticina by deep sequencing and identification of their potential targets in wheat. Functional Integrative Genomics. 19:391-407.

1. c) Funded research project of last 5 years with completion date - Govt. & Industry:

ICMR-DHR scientist research grant entitled “Genome-wide identification of Liquid-Liquid Phase Separation (LLPS)-related gene signature as potential therapeutic biomarker for breast cancer progression” of 30 lakh 92023-2025)

1. d) Details of Commercialization / Technology transfer, if any: None
2. e) Patent / Copyright, if any: None

Name of the Faculty member: Dr. Shilpi Gupta

1. b) Total Research Publications - last 5 years
2. Kumar P, Gupta S, Das AM, Das BC: Towards global elimination of cervical cancer in all groups of women. The Lancet Oncology 2019, 20(5):e237.
3. Chandel V, Raj S, Kumar P, Gupta S, Dhasmana A, Kesari KK, Ruokolainen J, Mehra P, Das BC, Kamal MA: Metabolic regulation in HPV associated head and neck squamous cell carcinoma. Life sciences 2020, 258:118236.
4. Gupta S, Kumar P, Das BC: HPV+ ve/− ve oral-tongue cancer stem cells: a potential target for relapse-free therapy. Translational Oncology 2021, 14(1):100919.
5. Gupta S, Kumar P, Das BC: Challenges and opportunities to making Indian women cervical cancer free. Indian Journal of Medical Research 2023, 158(5&6):470-475.
6. Kumar P, Gupta S, Das BC: Saliva as a potential non-invasive liquid biopsy for early and easy diagnosis/prognosis of head and neck cancer. Translational oncology 2024, 40:101827.
7. Kumar P, Lakhera R, Aggarwal S, Gupta S: Unlocking the Therapeutic Potential of Oral Cancer Stem Cell-Derived Exosomes. Biomedicines 2024, 12(8):1809.
8. shilpi gupta BCd: Safeguarding and Empowering Our Women. Science India 2024, 19(94):8-11.

c). Funded research project of last 5 years with completion date - Govt. & Industry

1. PI:(2024-2026 )"Evaluating the Chemo-sensitizing and Therapeutic Effects of Aspirin and Curcumin Combination in Oral Cancer and Reduction of Adverse Effects Induced by Anti-Cancer Drugs." 15.36 Lakh - CST-UT.
2. PI:(2022-2024) “Deciphering BMI-1 Protein in Cancer Stem Cells as Potential Therapeutic Target for Oral-Tongue Cancer” 31.14 Lakh- ICMR -DHR Young Scientist

d). Details of Commercialization / Technology transfer, if any: None

e). Patent / Copyright, if any: None

f). MoUs - None

Name of the Faculty member: Dr. Manoj Kumar

1. b) Total Research Publications - last 5 years

1. Hypothesis: Androgen receptor/Aurora A kinase/NF-κB signaling axis induce inflammatory response during polycystic ovarian syndrome progression. Kumar M, Medical Hypotheses, (2024), 184, 111286, ISSN: 0306-9877 (Impact factor:4.7)

1. Multifunctional human chromatin protein PC4 is downregulated in Breast Cancer to promote disease progression: Implications of miR-29a, Sikder S, Kumari S, Kumar M, Sen S, Singhal N, Chellappan S, Godbole M, Chandrani P, Dutt A, Gopinath K, Kundu TK, Oncotarget, (2019), 10( 64), 6855-6869,ISSN: 1949-2553 (Impact factor 5.1)

1. The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis, Singh S *, Kumar M *, Kumar S *, Sen S, Upadhyay P, Bhattacharjee S, Naveen M, Tomar VS, Roy S, Dutt A, and Kundu TK, Journal of Biological Chemistry (JBC), (2019), 294, 14081- 14095, ISSN: 0021-9258, *equal first author. (Impact factor 4.4)

1. Functional interplay between YY1 and CARM1 promotes oral carcinogenesis, Behera AK, Kumar M, Shanmugam MK, Bhattacharya A, Rao VJ, Bhat A, Vasudevan M, Gopinath KS, Mohiyuddin A, Chatterjee A, Sethi G, Kundu TK, Oncotarget, (2019),10(38), 3709-3724, ISSN:1949-2553 (Impact factor 5.1)

1. c) Funded research project of last 5 years with completion date - Govt. & Industry

1. SERB-TARE funded research project entitled “Role of Aurora kinases (A, B and C) in Gallbladder cancer metastasis and maintenance of cancer stem-like cells: Implication in Chemo-resistance” as PI (Approved in 2019 and grant returned to SERB) 18.3 Lakhs

1. ICMR funded research project entitled “Understanding the role of GCN5, lysine acetyltransferase in gallbladder cancer progression and synthesis of novel quinoline based compounds as its inhibitor as a therapeutic intervention” as PI (Approved in 2020 but grant not released). 31.2 Lakhs

1. DHR funded research project entitled “Understanding the role of Aurora A kinase in Gallbladder cancer progression and Maintenance of cancer stem-like cells: Implication in early Diagnosis and Chemo-resistance” as Mentor for DHR Women Scientist: 46.2 Lakhs (ongoing 2024-2027)

d). Details of Commercialization / Technology transfer, if any: None

1. e) Patent / Copyright, if any: none

S. No.	Department	Year (2015-2020)	Title of publications	Broad area	Impact factor
1	AIMMSCR	2020	Shilpi Gupta, Prabhat Kumar, Ankan M. Das, D. K. Gupta, Bhudev C. Das. Human viruses: infection, prevention and potential target(s) for therapy – A comprehensive review. In: Human Viruses: Diseases, Treatments and Vaccines: The New Insights Edited by Shamim I. Ahmad (2021). Springer and Taylor & Francis-CRC Press UKÂ	Virology and therapeutics	In Press
2	AIMMSCR	2020	Aftab, Mehreen, Satish Poojari, Vaishnavi Seshan, Sachin Kumar, Pallavi Agarwal, Simran Tandon, Vijay Zutshi, and Bhudev Das. "Urine miRNA signature as a potential non-invasive diagnostic and prognostic biomarker in cervical cancer." Scientific Reports	Molecular diagnostics	4.12
3	AIMMSCR	2020	Kirtonia A, Gala K, Fernandes SA, Pandya G, Pandey AK, Sethi G, Khattar E, Garg M*. Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics. Seminar in Cancer Biology 2020; 5:S1044-579X(20)30094-8. https://doi.org/10.1016/j.semcancer.2020.04.006. Â	Cancer therapeutics	11.09
4	AIMMSCR	2020	Gupta B, Sadaria D, Warrier VU, Kirtonia A, Kant R, Awasthi A, Baligar P, Paul JK, Yuba E, Sethi G, Garg M*, Gupta RK. Plant lectins and their usage in preparing targeted nanovaccines for cancer immunotherapy. Seminar in Cancer Biology 2020;5: S1044-579X(20)30038-49.	Nanovaccines	11.09
5	AIMMSCR	2020	Manoj Garg, Muthu K. Shanmugam, Vipul Bhardwaj, Akul Goel, Rajat Gupta, Arundhiti Sharma, Prakash Baligar, Alan Prem Kumar, Boon Cher Goh, Lingzhi Wang, Gautam Sethi. The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy. Medicinal Research Reviews. DOI: 10.1002/med.21761, 1-46, 2020. (Impact Factor: 9.75).	Cancer prevention and therapy	9.7
6	AIMMSCR	2020	Garg M, Shanmugam MK, Bhardwaj V, Goel A, Gupta R, Sharma A, Baligar P, Kumar AP, Goh BC, Wang L, Sethi G. The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy. Med Res Rev. 2020 Dec 1. doi: 10.1002/med.21761.	Oncogenesis	9.3
7	AIMMSCR	2020	XueqinGao, ZhuangJin, XiangyuTan, ChongZhang, ChenmingZou, WeiZhang, JiahuiDing, Bhudev C.Das, KonstantinSeverinov, Inga Isabel Hitzeroth, Priya Ranjan Debata, DanHe, XinMa, XunTian, QingleiGao, JunWu, RuiTian, ZifengCui, ZhengHu, Hyperbranched poly(β-amino ester) based polyplex nanopaticles for delivery of CRISPR/Cas9 system and treatment of HPV, infection associated cervical cancer, Journal of Controlled Release, doi.org/10.1016/j.jconrel.2020.02.045	genome editing	7.94
8	AIMMSCR	2020	Pandya G, Kirtonia A, Sethi G, Pandey AK, Garg M. A The implication of long non-coding RNAs in the diagnosis, pathogenesis and drug resistance of pancreatic ductal adenocarcinoma and their possible therapeutic potential. BBA Reviews on Cancer 2020; 1874(2): 188423.	Pancreatic cancer and long non-coding RNA	7.4
9	AIMMSCR	2020	Shermane Lim YW, Xiang X, Garg M, Le MT, Li-Ann Wong A, Wang L, Goh BC. The double-edged sword of H19 lncRNA: Insights into cancer therapy. Cancer Letters 2020; 19:S0304-3835(20)30598-X.Â	Long Non coding RNA	7.4
10	AIMMSCR	2020	Morgan D, Garg M, Tergaonkar V, Tan SY, Sethi G. Pharmacological significance of the non-canonical NF-κB pathway in tumorigenesis. Biochimica Biophysica Acta Review on Cancer. 2020 Dec;1874(2):188449.Â	Tumor Biology	7.4
11	AIMMSCR	2020	Evaluating the current status of protein kinase C (PKC)-protein kinase D (PKD) signalling axis as a novel therapeutic target in ovarian cancer. Tyagi K, Roy A*, Biochim Biophys Acta Rev Cancer, 2020 Dec 28;1875(1):188496. (IF: 7.4. *Corresponding author)	molecular therapeutics	7.4
12	AIMMSCR	2020	Kirtonia A, Sethi G, Garg M*. The multifaceted role of reactive oxygen species in tumorigenesis. Cell Mol Life Sci. 2020 May 1. doi: 10.1007/s00018-020-03536-5.	ROS and Tumorigenesis	7.01
13	AIMMSCR	2020	Lee JH, Mohan CD, Deivasigamani A, Jung YY, Rangappa S, Basappa S, Chinnathambi A, Alahmadi TA, Alharbi SA, Garg M, Lin ZX, Rangappa KS, Sethi G, Hui, KM, Ahn KS, Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma. Journal of Advanced Research 2020; 26:83-94.	STAT3 inhibitor in Liver Cancer	7
14	AIMMSCR	2020	Chansi, Pragadeeshwara Rao R, Irani Mukherjee, Tinku Basu, Lalit M Bharadwaj, “Metal Organic Framework steered electrosynthesis of anisotropic gold nanorod for specific sensing of organophosphate pesticides in vegetables collected from field” J. Nanoscale, 2020, DOI: 10.1039/D0NR04480F	nanocomposites	6.8
15	AIMMSCR	2020	R Pragadeeshwara Rao, Shalini Sharma, Tithi Mehrotra, Rajashree Das, Ranjit Kumar, Rachana Singh, Indrajit Roy and Basu Tinku, “Rapid Electrochemical Monitoring of Bacterial Respiration for Gram-Positive and Gram-Negative Microbes: Potential Application in Antimicrobial Susceptibility Testing” Anal. Chem. (2020) 92, 6, 4266–4274, DOI: 10.1021/acs.analchem.9b04810Â	biosensors	6.7
16	AIMMSCR	2020	Fernandes SG, Dsouza R, Pandya G, Kirtonia A, Tergaonkar V, Lee SY, Garg M, Khattar E. Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential. Cancers (Basel). 2020 Jul 14;12(7):E1901. doi: 10.3390/cancers12071901.	Telomere and cancers	6.5
17	AIMMSCR	2020	He Q, Toh JD, Ero R, Qiao Z, Kumar V, Serra A, Tan J, Sze SK, Gao YG (2020). The unusual di-domain structure of Dunaliella salina glycerol-3-phosphate dehydrogenase enables direct conversion of dihydroxyacetone phosphate to glycerol. Plant J. 102(1):153-164.	enzymology	5.8
19	AIMMSCR	2020	Niu, Gang, Zhuang Jin, Chong Zhang, Dan He, Xueqin Gao, Chenming Zou, Wei Zhang, Bhudev Das et al. "An effective vaginal gel to deliver CRISPR/Cas9 system encapsulated in poly (β-amino ester) nanoparticles for vaginal gene therapy." EBioMedicine 58 (2020)	genome editing	5.73
20	AIMMSCR	2020	Mirzaei S, Fekri HS, Hashemi F, Hushmandi K, Mohammadinejad R, Ashrafizadeh M, Zarrabi A, Garg M. Venom peptides in cancer therapy: An updated review on cellular and molecular aspects. Pharmacological Research. 2020 Dec 1:105327.	Venom Peptides	5.6
21	AIMMSCR	2020	Pal S, Garg M, Pandey AK. Deciphering the mounting complexity of the p53 regulated network in correlation to long non-coding RNAs (lncRNAs) in ovarian cancer. Cells 2020;9(3). Pii:E527. Â	LncRNA in Ovarian Cancer	5.6
22	AIMMSCR	2020	Kirtonia A, Pandya G, Sethi G, Pandey AK, Das BC, Garg M. A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia. J Mol Med (Berl). 2020; 98(8):1069-1091.	Genomics in AML	5.5
23	AIMMSCR	2020	Kansara S, Pandey V, Lobie PE, Sethi G, Garg M, Pandey AK. Mechanistic Involvement of Long Non-Coding RNAs in Oncotherapeutics Resistance in Triple-Negative Breast Cancer. Cells (MDPI) 2020; 9(6):E1511.	LncRNA and TNBC	5.5
24	AIMMSCR	2020	Sneha S, Nagare RP, Sidhanth C, Krishnapriya S, Garg M, Ramachandran B, Murhekr K, Sundersingh S, Ganesan TS. The hedgehog pathway regulates cancer stem cells in serous adenocarcinoma of the ovary. Cellular Oncology 2020; May 8. Doi: 10.1007/s13402-020-00504-w.Â	Hedgehog signaling in ovarian cancer	5
25	AIMMSCR	2020	Kirtonia, Anuradha, Gouri Pandya, Gautam Sethi, Amit Kumar Pandey, Bhudev C. Das, and Manoj Garg. "A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia." Journal of Molecular Medicine	personalised medicines	4.93
26	AIMMSCR	2020	Subrata K Pore, Hahm ER, Kim S, Singh KB et al, A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption. Mol Cancer Ther .19(2), 420-431	Breast cancer bone metastasis, Phytochemicals	4.9
27	AIMMSCR	2020	Chen, Yili, Hongye Jiang, Ting Wang, Dan He, Rui Tian, Zifeng Cui, Xun Tian, Bhudev Das et al. "In vitro and in vivo growth inhibition of human cervical cancer cells via human papillomavirus E6/E7 mRNAs’ cleavage by CRISPR/Cas13a system." Antiviral research 178 (2020): 104794.	genome editing	4.9
28	AIMMSCR	2020	 Manoj Kumar*, Komal Sharma*, Akhilesh K. Yadav*, Kajal Kanchan*, Madhu Baghel, Suneel Kateriya and Girdhar K. Pandey (2020) Genome-wide identification and biochemical characterization of calcineurin B-like calcium sensor proteins in Chlamydomonas reinhardtii. Biochemical Journal 477, 1879–1892. (*equal Contribution) [IF: 4.8]	protein biochemistry	4.8
29	AIMMSCR	2020	Ashrafizadeh M, Zarrabi A, Saberifar S, Hashemi F, Hushmandi K, Hashemi F, Moghadam ER, Mohammadinejad R, Najafi M, Garg M*. Nobiletin in cancer therapy: How this plant derived-natural compound targets various oncogene and onco-suppressor pathways. Biomedicines; 2020, Accepted.Â	cancer therapeutics	4.7
30	AIMMSCR	2020	Kumar S, Sharma PP, Shankar U, Kumar D et al. 2020. Discovery of New Hydroxyethylamine Analogs against 3CL pro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure-Activity Relationship Studies. J Chem Inf Model. 10.1021/acs.jcim.0c00326Â	Virology	4.5
31	AIMMSCR	2020	Chandel V, Raj S, Rathi B, Kumar D. 2020. In silico identification of potent FDA approved drugs against Coronavirus COVID-19 main protease: A drug repurposing approach. Chemical Biology Letters. 7(3), 166‐175.	Virology	4.5
32	AIMMSCR	2020	Chandel V, Raj S, Srivastava A, Kumar D. 2020. In-silico interactions of active Phytochemicals with c-MYC EGFR and ERBB2 oncoproteins. Chemical Biology Letters. 7(1), 47‐54.Â	in silico studies	4.5
33	AIMMSCR	2020	Sharma S, Ghufran S M, Ghose S, Biswas S*. Cytoplasmic vacuolation with endoplasmic reticulum stress directs sorafenib induced non-apoptotic cell death in hepatic stellate cells Scientific Report (2020) SREP-18-33528	Liver Fibrosis, Scientific Report	4.1
34	AIMMSCR	2020	Aditi Chauhan, Manoj Kumar, Awanish Kumar, and Kajal Kanchan* (2020) Comprehensive review on mechanism of action, resistance and evolution of antimycobacterial drugs. Life Science Journal (under review). [IF 3.9]	Antimycobacterial drugs	3.9
35	AIMMSCR	2020	Tayal N, Ghufran SM, Srivastava P, Kandhwal S, Biswas S and Srivastava N. Anti-Angiogenic Activity of Columbin: A Diterpenoid from Tinospora Cordifolia. IJBPAS (2020) 9(3): 540-552	Angiogenesis, Pharmacy and allied SciencesÂ	3.8
36	AIMMSCR	2020	Chansi, Rashi Bhardwaj, R. Pragadeeshwara Rao, Irani Mukherjee, Pawan Kumar Aggarwal, Tinku Basu, Lalit M Bharadwaj, “Layered construction of nano immuno-hybrid embedded MOF as an electrochemical sensor for rapid quantification of total pesticides load in vegetable extract” J. Electroanl. Chem. 873 (2020) 114386, DOI: 10.1016/j.jelechem.2020.114386Â	nanocomposites	3.8
37	AIMMSCR	2020	Nadella V, Garg M, Kapoor S, Barwal TS, Jain A, Prakash H. Emerging neo adjuvants for harnessing therapeutic potential of M1 tumor associated macrophages (TAM) against solid tumors: Enusage of plasticity. Ann Transl Med June, 2020,8	Tumor Microenvironment	3.7
38	AIMMSCR	2020	Chandel, Vaishali, Sibi Raj, Prabhat Kumar, Shilpi Gupta, Anupam Dhasmana, Kavindra Kumar Kesari, Bhudev Das et al. "Metabolic regulation in HPV associated head and neck squamous cell carcinoma." Life Sciences	virus mediated cancers	3.64
39	AIMMSCR	2020	Narula S, Tandon S, Kumar D, Varshney S, Adlakha K, Sengupta S, Singh SK, Tandon C. Human kidney stone matrix proteins alleviate hyperoxaluria induced renal stress by targeting cell-crystal interactions. Life Sci. (2020 )1;262:118498. doi: 10.1016/j.lfs.2020.118498	Antilithiatic proteins from kidney matrix	3.6
40	AIMMSCR	2020	Narula S, Tandon S, Kumar D et al. 2020. Human kidney stone matrix proteins alleviate hyperoxaluria induced renal stress by targeting cell-crystal interactions. Life Sciences. https://doi.org/10.1016/j.lfs.2020.118498Â Â	disease biology	3.6
41	AIMMSCR	2020	Satyam R, Jha NK, Kar R et al. 2020. Deciphering the SSR incidences across viral members of Coronaviridae family. Chemico-Biological Interactions. https://doi.org/10.1016/j.cbi.2020.109226	virology	3.6
42	AIMMSCR	2020	Raj S, Chandel V, et al. 2020 Molecular mechanisms of interplay between autophagy and metabolism in cancer, Life Sciences. https://doi.org/10.1016/j.lfs.2020.118184	cancer mechanisms	3.6
43	AIMMSCR	2020	Chandel V, Raj S, et al. 2020. Metabolic regulation in HPV associated head and neck squamous cell carcinoma, Life Sciences. https://doi.org/10.1016/j.lfs.2020.118236	virus mediated cancers	3.6
44	AIMMSCR	2020	Nadella V, Garg M, Kapoor S, Barwal TS, Jain A, Prakash H. Emerging neo adjuvants for harnessing therapeutic potential of M1 tumor associated macrophages (TAM) against solid tumors: Enusage of plasticity. Ann Transl Med. 2020 Aug;8(16):1029.	cancer immunology	3.6
45	AIMMSCR	2020	Gupta, Shilpi, Prabhat Kumar, and Bhudev C. Das. "HPV+ ve/− ve oral-tongue cancer stem cells: A potential target for relapse-free therapy." Translational oncology 14, no. 1 (2020)	cancer recurrence	3.55
46	AIMMSCR	2020	Subrata K Pore*, Ganguly A, Sau S, Godeshala S et al, N-end rule pathway inhibitor sensitizes cancer cells to antineoplastic agents by regulating XIAP and RAD21 protein expression. 121(1), 804-815 (* corresponding)	N-end rule pathway’s role in cancer	3.5
47	AIMMSCR	2020	Tyagi R., et al. 2020. Development of potential proteasome inhibitors against Mycobacterium tuberculosis. Journal of Biomolecular Structure & Dynamics. https://doi.org/10.1080/07391102.2020.1835722Â Â	host pathogen interaction	3.2
48	AIMMSCR	2020	Chandel V, Raj S, Rathi B, Choudhary R, Kumar D. 2020. Structure-based drug repurposing for targeting Nsp9 replicase and spike proteins of severe acute respiratory syndrome coronavirus 2. Journal of Biomolecular Structure & Dynamics. https://doi.org/10.1080/07391102.2020.1811773	virology	3.2
49	AIMMSCR	2020	Isha Fuletra, Chansi Gupta, Sumaya Nisar, Rashi Bharadwaj, Punya Saluja, Sheetal K. Bhardwaj, K. Asokan, Tinku Basu “Self-assembled gold nano islands for precise electrochemical sensing of trace level of arsenic in water” J. Groundwater for Sustainable Development, 2020, DOI: 10.1016/j.gsd.2020.100528	nanosensors	3
50	AIMMSCR	2020	Ashrafizadeh M, Javanmardi S, Moradi-Ozarlou M, Mohammadinejad R, Farkhondeh T, Samarghandian S, Garg M*. Natural products and phytochemical nanoformulations targeting mitochondria in oncotherapy: an updated review on resveratrol. Bioscience Reports. 2020 Apr 30;40(4).	Phytochemicals	2.9
51	AIMMSCR	2020	Jaiswal G and Kumar V# (2020). In-silico design of a potential inhibitor of SARS-CoV-2 S protein. PLoS One, 15(10): e0240004	Computational chemistry	2.8
52	AIMMSCR	2020	Kumar D., et al. 2020. Stem Cell Based Preclinical Drug Development and Toxicity Prediction. Current Pharmaceutical Design. https://doi.org/10.2174/1381612826666201019104712Â	stem cells for toxicity testing	2.4
53	AIMMSCR	2020	Shreyas Vasantham, Ruby Alhans, Chaitali Singhal, Shalini Nagabooshanam, Sumaya Nissar, Tinku Basu, Sekhar C Ray, Shikha Wadhwa, Jagriti Narang, Ashish Mathur, “Paper based point of care immunosensor for the impedimetric detection of cardiac troponin I biomarker” J. Biomedical Microdevices 22 (2020) 1, 6, DOI: 10.1007/s10544-019-0463-0Â	immunosensors	2.3
54	AIMMSCR	2020	Kumar D, Baligar P, Srivastav R, Narad P, Raj S, Tandon C, Tandon S. Stem Cell Based Preclinical Drug Development and Toxicity Prediction. Current Pharmaceutical Design (2020)26; 1: https://doi.org/10.2174/1381612826666201019104712	stem cell biology	2.2
55	AIMMSCR	2020	Chatterjee A, Rajarshi K, Ghosh H, Khan R, Kapoor S* and Shashikant Ray. An intimate alliance of DNA-damage response network with cell-cycle checkpoints amid events of uncontrolled cellular proliferation- a mini review. Endocrine, Metabolic & Immune Disorders-Drug Targets, 2020 (doi: 10.2174/1871530320999200918143856.)	drug targets	2
56	AIMMSCR	2020	Chandel V, Kumar D. 2020. Targeting Signalling Cross-Talk between Cancer Cells and Cancer Associate Fibroblast through Monocarboxylate Transporters in Head and Neck Cancer, Anti-Cancer Agents in Medicinal Chemistry: Bentham Science Publishers, DOI : 10.2174/1871520620666200721135230	tumor microenvironment	2.06
57	AIMMSCR/AIB	2020	Gaur V, Chaudhary S, Tyagi A, Agarwal S, Sharawat SK, Sarkar S, Singh H, Bakhshi S, Sharma P*, Kumar S*. Dysregulation of miRNA expression and their prognostic significance in paediatric cytogenetically normal acute myeloid leukaemia. Br J Haematol. 188(6):e90-e94.	miRNA biology	5.02
58	AIMMSCR/AIB	2020	Anupriya Chatterjee, Shradha Nirwan, Prasun Bandyopadhyay, Abha Agnihotri, Pankaj Sharma, Abdin Malik Z, Neeraj, Shrivastava. Genomic and Molecular Perspectives of Host-pathogen Interaction and Resistance Strategies against White Rust in Oilseed Mustard. Curr. Genom.  21 (3): 179-193.	functional genomics	2.63
59	AIMMSCR/AIB	2020	Shikha Yadav, Nakul Dev S Yadav, Atish Gheware, Ankur Kulshreshtha, Pankaj Sharma*, V P Singh. Oral Feeding of Cow Milk Containing A1 Variant of β Casein Induces Pulmonary Inflammation in Male Balb/c Mice. Sci Rep. 10(1):8053-60.	Immunology	4.12
60	AIMMSCR/AIB	2020	Subhashini Bharathala, Rajni Singh*, Pankaj Sharma*. Controlled release and enhanced biological activity of chitosan-fabricated carbenoxolone nanoparticles. Int J Biol Macromol.164:45-52.	Nanomedicine	5.16
61	AIMMSCR/AIB	2020	Shrishty Bakshi, Samriddhi Mehta, Tushar Kumeria, Sangeeta Choudhury, Sudeep Bose,* and Ranu Nayak* Rapid uniform immobilization and picomolar detection of proteins using hyper-branched nanostructured gold sensing electrode Sensors & Actuators: B. Chemical 326	Cancer Diagnostics	7.1
62	AIMMSCR	2019	Prabhat Kumar, Shilpi Gupta, Ankan Mukherjee Das, Bhudev C Das, Towards global elimination of cervical cancer in all groups of women, The Lancet Oncology 20(5), e237,2019	Cervical Cancer	33.7
63	AIMMSCR	2019	Shakeel A, Bhattacharya R, Jeevanandham S, Kochhar D, Singh A, Mehra L, Ghufran M, Garg P, Sangam S, Biswas S et al Graphene Quantum Dots in the Game of Directing Polymer Self-Assembly to Exotic Kagome Lattice and Janus Nanostructures. ACS Nano (2019)Â Â 13(8):9397-9407.	Nano delivery and Cancer	14.5
64	AIMMSCR	2019	Sibi Raj, Sartaj Khuranaa, Ramesh Choudhari et al. 2019. Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy. Seminars in Cancer Biology https://doi.org/10.1016/j.semcancer.2019.11.002	nano delivery and Cancer	11
65	AIMMSCR	2019	Palazzolo S, Hadla M, Spena C. R, Caligiuri I, Rotondo R, Abdeel M, Kumar V, Corona G, Canzonieri V, Toffoli G and Rizzolio F “An effective Multi-Stage Liposomal DNA Origami Nanosystem for IN Vivo Cancer Therapy” Cancers, 11, 1-12, 2019	DNA nanotechnology and drug delivery	6.2
66	AIMMSCR	2019	Sheetal K. Bhardwaj, Ruchika Chauhan, Premlata Yadav, Subhasis Ghosh, Ajit K. Mahapatro, Jay Singh and Tinku Basu “Bi-enzyme functionalized electro-chemically reduced transparent graphene oxide platform for triglyceride detection” J. Biomater. Sci. (2019) 7, 1598 – 1606, DOI: 10.1039/c8bm01406j	biosensors	6.1
67	AIMMSCR	2019	Godara S, Lather V, Kirthanashri SV, Awasthi R, Pandita D. Lipid-PLGA hybrid nanoparticles of paclitaxel: Preparation, characterization, in vitro and in vivo evaluation. Materials Science and Engineering: C.	tissue Engineering	5.03
68	AIMMSCR	2019	Singh KB, Hahm ER, Subrata K Pore, and Singh SV. Leelamine is a Novel Lipogenesis Inhibitor in Prostate Cancer Cells In Vitro and In Vivo. 18(10), 1800-1810	molecular therapeutics	4.9
69	AIMMSCR	2019	Nayak TK, Vij R, Bruhova I, Shandilya J, Auerbach A. Efficiency measures the conversion of agonist binding energy into receptor conformational change. Journal of General Physiology. 2019; 151:465-477.Â	Acetylcholine receptor, ligand binding	4.2
70	AIMMSCR	2019	Kaushik J, Tandon S, Bhardwaj R, Kaur T, Singla SK, Kumar J, Tandon . Delving into the Antiurolithiatic Potential of Tribulus terrestris Extract Through -In Vivo Efficacy and Preclinical Safety Investigations in Wistar Rats. Sci Rep. (2019)Â 4;9(1):15969. doi: 10.1038/s41598-019-52398-w	In vivo efficacy against urolithiasis with plant extract	4.2
71	AIMMSCR	2019	Bindhya S, Sidhanth C, Shabna A, Krishnapriya S, Garg M, Ganesan TS. Induced pluripotent stem cells: A new strategy to model human cancer. International Journal of Biochemistry & Cell Biology 2019: 14;107:62-68.Â	stem cells IPSCs	4.2
72	AIMMSCR	2019	Asif A, Saleheen B, Satish S.P, Kumar D, Yuvraj S N, 2019. Effect of incorporation of Montmorillonite on Xylan/Chitosan conjugate scaffold. Colloids and Surfaces B: Biointerfaces 1(180) 75-82	tissue Engineering	3.9
73	AIMMSCR	2019	Palazzolo S, Hadla M, Spena C. R, Bayda S, Kumar V, Re F. L, Caligiuri I, Romano F, Corona G, Canzonieri V, Toffoli G and Rizzolio F “A proof-of-concept multi-stage biomimetic liposomal DNA origami nanosystem for the remote loading of doxorubicin” ACS Med. Chem. Lett., 10, 517-521,2019.  Â	DNA nanotechnology and drug delivery	3.8
74	AIMMSCR	2019	Reshma Rani, Vinit Kumar* and Flavia Rizzolio “ Fluorescent Carbon Nanoparticles in Medicine for Cancer Therapy: An Update” ACS Med. Chem. Lett., 9, 4-5, 2018.	Bioimaging and drug deliveryÂ	3.8
75	AIMMSCR	2019	Yunhui Jiang, Chengyi Zhu, Dan He, Qinglei Gao , Xun Tian, Xin Ma, Jun Wu, Bhudev C. Das, Konstantin Severinov, Inga Isabel Hitzeroth, Priya Ranjan Debata, Rong Liu, Liang Zou, Long Shi, Hua Xu, Kaixiu Wang, Yuxian Bao, Leung Ross Ka-Kit, Zeshan You‡, Zifeng Cui and Zheng Hu, Cytological Immunostaining of HMGA2, LRP1B, and TP63 as Potential Biomarkers for Triaging Human Papillomavirus-Positive Women, Translational Oncology, doi.org/10.1016/j.tranon.2019.04.012	molecular biomarkers	3.5
76	AIMMSCR	2019	Anukriti, Anupam D, Swati U, Pallavi S, et al. 2019. Investigation of Precise Molecular Mechanistic Action of Tobacco-Associated Carcinogen ‘NNK’ Induced Carcinogenesis: A System Biology Approach. Genes. 10(8), 564.Â	carcinomesis	3.4
77	AIMMSCR	2019	Oncogenic potential of nucleoporins in non-hematological cancers: recent update beyond chromosome translocation and gene fusion. Roy A*, Narayan G. J Cancer Res Clin Oncol. 2019 Oct 25. 145(12), 2901-2910. Review. (IF: 3.332. *Corresponding author)	Non-hematological cancers	3.3
78	AIMMSCR	2019	Warrier VU, Makandar AI, Garg M*, Sethi G, Kant R, Paul JK, Yuba E, Gupta RK. Engineering anti-cancer nanovaccine based on antigen cross presentation. Bioscience Report 2019; 39(10).	Immunotherapy	2.9
79	AIMMSCR	2019	Shirish Shukla1a, Mohit Jadli, Kulbhushan Thakur,, Gauri Shishodia, Sutapa Mahata, Seemi Farhat Basir, Bhudev Chandra Das, Alok Chandra Bharti. Level of phospho-STAT3 (Tyr705) correlates with copy number and physical state of human papillomavirus 16 genome in cervical precancer and cancer lesions, Plos One 14(9): e0222089,2019	Cervical Cancer	2.87
80	AIMMSCR	2019	Ero R , Kumar V, Su WX, Gao YG (2019). Ribosome protection mechanism by ABC-F family of proteins. Protein Science (Cover Story), 28(4): 684-693	Ribosome	2.7
81	AIMMSCR	2019	Jyoti S, Tandon S. Disruption of mitochondrial membrane potential coupled with alterations in cardiac biomarker expression as early cardiotoxic signatures in human ES cell-derived cardiac cells. Hum Exp Toxicol. (2019) Jun 10:960327119855132.	Early cardiotoxic signatures in hES cell-derived cardiac cells	2.1
82	AIMMSCR/AIB	2019	V Gaur, S Chaudhary, A Tyagi, S Bakhshi, P Sharma*, S Kumar*. 161PDifferential expression of various miRNAs in pediatric cytogenetically normal acute myeloid leukemia (CN-AML). Ann. Oncol. 30 (Suppl. 5). 161P.	miRNA biology	18.27
83	AIMMSCR/AIB	2019	Shrishty Bakshi, Kritika Pandey, Sudeep Bose, Gunjan Debarati Paul, Ranu Nayaka, Permanent superhydrophilic surface modification in microporouspolydimethylsiloxane sponge for multi-functional applications Journal of Colloid and Interface Science 2019 552 ; 34-42Â	nanoformulation	6.3
84	AIMMSCR/AIB	2019	Sudeep Bose et al., Pit-1 binding adjacent to an E-box in the PRL promoter is necessary for prolactin gene expression pulse activity Neurochemical Research, 2016 Jun;41(6):139	neurochemicals	2.8
85	AIMMSCR	2018	Varshney A, Panda JJ, Singh AK, Yadav N, Bihari C, Biswas S,. Sarin SK, Chauhan VS (2018). Targeted delivery of miR-199a-3p using self-assembled dipeptide nanoparticles efficiently reduces hepatocellular carcinoma. Hepatology 67, 1392-1407	Targeted Therapy of Liver Cancer, Hepatology	14.6
86	AIMMSCR	2018	Kumar D, et al., 2018. Cancer-associated fibroblasts drive glycolysis in a targetable signaling loop implicated in head and neck squamous cell carcinoma progression. Cancer Research. 10.1158/0008-5472.CAN-17-1076.Â	tumor microenvironment	10
87	AIMMSCR	2018	Su WX*, Kumar V*, Ding Y*, Ero R, Serra A, Lee BST, Wong ASW, Shi J, Sze SK, Yang L, Gao YG (2018) Ribosome protection by antibiotic resistance ATP-binding cassette protein. Proc Natl Acad Sci U S A, 115(20):5157-5162 (*equal contribution)	cell biology	9.7
88	AIMMSCR	2018	Subrata K Pore, Hahm ER, Latoche JD, Anderson CJ, Shuai Y, and Singh SV. Prevention of breast cancer-induced osteolytic bone resorption by benzyl isothiocyanate. 39(2):134-145	Breast cancer bone metastasis, Phytochemicals	5.1
89	AIMMSCR	2018	Nasreen Bano, Manisha Yadav and Bhudev Chandra Das, Differential inhibitory effects of curcumin between HPV+ve and HPV-ve oral cancer stem cells, Frontiers in Oncology-Molecular and Cellular Oncology, doi: 10.3389/fonc.2018.00412. 2018	Oral Cancer	4.8
90	AIMMSCR	2018	Kapoor S, Srivastava S, Panda D. Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Sci Rep. 2018;8:12363.	Cancer Chemotherapy	4.6
91	AIMMSCR	2018	 Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway. Ye J, Das S, Roy A, Wei W, Huang H, Lorenz-Guertin JM, Xu Q, Jacob TC, Wang B, Sun D, Wang QJ. Mol Neurobiol. 2019 Mar;56(3):2123-2136. doi: 10.1007/s12035-018-1198-2. Epub 2018 Jul 11. (IF: 4.586)	neuroprotection	4.5
92	AIMMSCR	2018	Protein Kinase D2 Modulates Cell Cycle by Stabilizing Aurora A Kinase at Centrosomes. Roy A, Veroli MV, Prasad S, Wang QJ. Mol Cancer Res. 2018 Nov;16(11):1785-1797. doi: 10.1158/1541-7786.MCR-18-0641. Epub 2018 Jul 17. (IF: 4.484)	cellcycle and mechanisms	4.4
93	AIMMSCR	2018	Srivastav R, Sharma R, Tandon S, Tandon C.Role of DHH superfamily proteins in nucleic acids metabolism and stress tolerance in prokaryotes and eukaryotes.Int J Biol Macromol. (2019) Apr 15;127:66-75.Â	MMP as biomarkers in CKD	4.2
94	AIMMSCR	2018	Vishwakarma V, New J1, Kumar D, et al., 2018. Potent Antitumor Effects of a Combination of Three Nutraceutical Compounds. Scientific Reports. 15;8(1):12163.Â	Nutraceuticals	4.1
95	AIMMSCR	2018	Jain A, Singh SK, Arya SK, Kundu SC, Kapoor S*. Protein Nanoparticles: Promising Platforms for Drug Delivery Applications. ACS Biomater. Sci. Eng.2018, 4,12,3939-3961	Drug Delivery	4.1
96	AIMMSCR	2018	Singh KB, Kim SH, Hahm ER, Subrata K Pore, Jacobs BL, Singh SV. Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism. 39:826-837	Prostate cancer, fatty acid metabolism, phytochemicals	4
97	AIMMSCR	2018	Shilpi Gupta, Prabhat Kumar, Nishi Sharma, Daman Saluja, Alok C. Bharti, Bhudev C. Das. Constitutive Activation of NF-κB p50/c-Rel Subunits Contribute in Tumor Aggressiveness and Metastasis during Tongue Carcinogenesis, Oncotarget, 2018, Vol. 9, (No. 68), pp: 33011-33029	carcinogenesis	3.7
98	AIMMSCR	2018	Jalota A, Kumar M, Das BC, Yadav AK, Chosdol K, Sinha S. A drug combination targeting hypoxia induced chemoresistance and stemness in glioma cells. Oncotarget. 6;9(26):18351, 2018	stem cell biology	3.7
99	AIMMSCR	2018	Ghose S *, Biswas S *, Kasturi Datta, Rakesh K. Tyagi Dynamic Hyaluronan drives liver endothelial cells towards angiogenesis. BMC Cancer (2018) 18:648	Angiogenesis in Liver, BMC Cancer	3.6
100	AIMMSCR	2018	Biswas S* and Ghose S. (2018). Divergent impact of Gender in Advancement of Liver injuries, diseases, and carcinogenesis. Frontier in Biosciences. 10:65-100.	Liver Diseases, Frontier in Biosciences	3.5
101	AIMMSCR	2018	Chien W, Sudo M, Ding LW, Sun QY, Wuensche P, Lee KL, Hattori N, Garg M, Xu L, Zheng Y, Gery S, Wongphayak S, Yang H, Baoglu E, Shacham S, Kauffman M, Mori, Koeffler HP. Functional Genome-wide screening identifies targets and pathways sensitizing pancreatic cancer cells to dasatinib. Journal of Cancer 2018;9(24):4762-4773.Â	functional genomics	3.5
102	AIMMSCR	2018	Sharma S, Ghufran SM, Ghose S, Biswas S*. Survivin inhibition limits TGF-β-induced fibrogenic responses of hepatic stellate cells. Cancer Medicine (2018) 7 (S1): 24Â	Liver Fibrosis, Cancer Medicine	3.4
103	AIMMSCR	2018	Gupta, Shilpi, Prabhat Kumar, and Bhudev C. Das. "HPV: Molecular pathways and targets." Current problems in cancer, 42, 2:161-174, 2018	Cervical Cancer	3.2
104	AIMMSCR	2018	Sidhanth C, Manasa P, Krishnapriya S, Sneha S, Bindhya S, Nagare RP, Garg M, Ganesan TS. A systematic understanding of signaling by ErbB2 in cancer using phosphoproteomics. Biochemistry & Cell Biology 2018; 96(3):295-305.	phosphoproteomics	3
105	AIMMSCR	2018	Nasreen Bano, Manisha Yadav, Bhudev C. Das.The role of NF-κB and miRNA in oral cancer and cancer stem cells with or without HPV16 infection. Plos One, 13(10): e0205518, 2018	cancer stem Cell	2.8
106	AIMMSCR	2018	Moushumi Suryavanshi · Anurag Mehta · Jiten Jaipuria · Dushyant Kumar · Gayatri Vishwakarma Manoj Kumar Panigrahi · Haristuti Verma · Mumtaz Saifi · Sanjeev Sharma · Simran Tandon· D. C. Doval, ·Bhudev C. Das. Clinical utility of RT‑PCR in assessing HER 2 gene expression versus traditional IHC and FISH in breast cancer patients, Breast Cancer, 25(4):416-430, 2018	Breast Cancer	2.25
107	AIMMSCR	2017	Prakash Baligar, Veena Kochat, Shailendra K. Arindkar, Snehashish Mukherjee, Zaffar Equbal, Swati Patel, Perumal Nagarajan, Sujata Mohanty, Jeffrey H. Teckman, Asok Mukhopadhyay. Bone marrow stem cell therapy partially ameliorates pathological consequences of liver in mice expressing mutant human α1-antitrypsin. Hepatology 2017, 65(4), 1319-1335. (IF- 14.6)	stem cell therapy	14.6
108	AIMMSCR	2017	Samanta SK, Sehrawat A, Kim SH, Hahm ER, Shuai Y, Roy R, Subrata K Pore et al, Disease subtype-independent biomarkers of breast cancer chemoprevention by the ayurvedic medicine phytochemical Withaferin. A. J Natl Cancer Inst. 2017, 109(6) doi: 10.1093/jnci/djw293	cancer biomarkers	11.4
109	AIMMSCR	2017	Ding LW, Sun QY, Tan KT, Chien W, Mayakonda A, Yeoh AE, Kawamata N, Nagata Y, Xiao JF, Loh XY, Lin DC, Garg M, Jiang YY, Xu L, Lim SL, Liu LZ, Madan V, Sanada M, Fernández LT, Preethi H, Lill M, Kantarjian HM, Kornblau SM, Miyano S, Liang DC, Ogawa S, Shih LY, Yang H, Koeffler HP. Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia. Cancer Research 2017; 77(2):390-400.Â	genomics and mutational analysis	10
110	AIMMSCR	2017	Sun QY, Ding LW, Tan KT, Chien W, Mayakonda A, Lin DC, Loh XY, Xiao JF, Meggendorfer M, Alpermann T, Garg M, Lim SL, Madan V, Hattori N, Nagata Y, Miyano S, Yeoh AE, Hou HA, Jiang YY, Takao S, Liu LZ, Tan SZ, Lill M, Hayashi M, Kinoshita A, Kantarijian HM, Kornblau SM, Ogawa S, Haferlach T, Yang H, Koeffler HP. Ordering of mutations in acute myeloid leukemia with partial tandem duplication of MLL (MLL-PTD). Leukemia 2017; 31(1):1-10	genomics and mutational analysis	8.66
111	AIMMSCR	2017	Bayda S, Hadla M , Kumar Vinit, Palazzolo S, Ambrosi E, Pontoglio E, Agostini M, Bendetti A, Riello R, Corona G, Toffoli G, Rizzolio F, “A bottom-up synthesis of carbon nanoparticles with better doxorubicin efficacy” J. Control. Release, 248, 144-152, 2017.	Drug delivery	7.9
112	AIMMSCR	2017	Protein kinase D signaling in cancer: A friend or foe? Roy A, Ye J, Deng F, Wang QJ. Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):283-294. doi: 10.1016/j.bbcan.2017.05.008. Epub 2017 May 31. Review. (IF: 7.4)	Protein Kinase	7.4
113	AIMMSCR	2017	U Sahu, A Choudhury, S Parvez, S Biswas, S Kar. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E.coli. Cell Death & Disease (2017) 8(3):e2667.	Cancer Stem Cell, Cell Death Diseases	6.4
114	AIMMSCR	2017	Kanojia D, Garg M, Martinez J, M T A, Luty SB, Doan NB, Said JW, Forscher C, Tyner JW, Koeffler HP. Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets. Journal of Hematology and Oncology 2017; 10(1):173.	drug screening	6.4
115	AIMMSCR	2017	Ding LW, Sun QY, Mayakonda A, Tan KT, Chien W, Lin DC, Jiang YY, Xu L, Garg M, Lao ZT, Lill M, Yeoh AE, Koeffler HP. Mutational profiling of acute lymphocytic leukemia with testicular relapse. Journal of Hematology and Oncology 2017; 10 (1):65	functional genomics	6.4
116	AIMMSCR	2017	Garg M*, Kanojia D, Mayakonda A, Said JW, Doan NB, Chien W, Ganesan TS, Chuang LS, Venkatachalam N, Baloglu E, Shacham S, Kauffman M, Koeffler HP. Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma. Oncotarget 2017; 8(5):7521-7532.Â	molecular therapeutics	6
117	AIMMSCR	2017	Kumar V (2017) Structure of elongation factor 4 bound to the ribosome Acta Crystallographica Section A: Foundations and Advances 73(a2):C1328-C1328	Ribosome	5.7
118	AIMMSCR	2017	Marsh LA, Carrera S, Shandilya J, Heesom KJ, Davidson AD, Medler KF, Roberts SG. BASP1 interacts with oestrogen receptor α and modifies the tamoxifen response. Cell Death & Disease. 2017; 8(5): e2771	Tumor suppressor, cancer therapeutics	5.6
119	AIMMSCR	2017	Garg M*, Kanojia D, Mayakonda A, Ganesan TS, Sadhanandhan B, Suresh S, S S, Nagare RP, Said JW, Doan NB, Ding LW, Baloglu E, Shacham S, Kauffman M, Koeffler HP. Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin. Scientific Reports 2017; 7(1):9749.Â	molecular therapeutics	5.5
120	AIMMSCR	2017	Rai A, Kapoor S, Naaz A, Kumar Santra M, Panda D. Enhanced stability of microtubules contributes in the development of colchicine resistance in MCF-7 cells. Biochem Pharmacol. 2017;132:38-47	Cancer Chemotherapy	5.1
121	AIMMSCR	2017	Garg M*, Kanojia D, Mayakonda A, Ganesan TS, Sadhanandhan B, Suresh S, S S, Nagare RP, Said JW, Doan NB, Ding LW, Baloglu E, Shacham S, Kauffman M, Koeffler HP. Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin. Scientific Reports 2017; 7(1):9749.	molecular therapeutics	4.5
122	AIMMSCR	2017	Sharma S, Kaufmann T, Biswas S * Impact of inhibitor of apoptosis proteins on immune modulation and inflammation. Immunology and Cell Biology (2017) 95(3):236-243.	Immunology and Cell Biology	4.4
123	AIMMSCR	2017	Rani R, Kumar Vinit*, “When will small molecule LDH inhibitors realize their potential in the cancer clinic?” Future Med Chem. 9, 113-115 2017.	Drug discovery	4
124	AIMMSCR	2017	Abhishek Tyag i, Kanchan Vishnoi, Harsimrut Kaur, Yogesh Srivastava, Bal Roy, Alok C. Bharti, Bhudev C. Das. Cervical cancer stem cells manifest radi resistance through upregulation of AP-1 activity, Nature Scientific Reports, 6;7(1):4781 2017	cancer stem cell biology	3.9
125	AIMMSCR	2017	Kochat V, Equbal Z, Baligar P, Kumar V, Srivastava M, Mukhopadhyay A. JMJD3 aids in reprogramming of bone marrow progenitor cells to hepatic phenotype through epigenetic activation of hepatic transcription factors. PLoS One. 2017, 12(3). (IF-3.80)	stem cell reprogramming	3.8
126	AIMMSCR	2017	Narula S, Tandon S, Baligar P, Singh SK, Tandon C. Human kidney stone matrix: Latent potential to restrain COM induced cytotoxicity and inflammatory response. Chem Biol Interact.( 2017) Oct 17. pii: S0009-2797(17)30718-4. doi: 10.1016/j.cbi.2017.10.018	Stone matrix proteins in COM injury	3.7
127	AIMMSCR	2017	Kashyap M, Subrata K Pore, de Groat WC, Chermansky C, Yoshimura N, Tyagi P. BDNF overexpression in bladder induces neuronal changes to mediate bladder overactivity. 315 (1): F45-F56	Bladder overactivity, Liposome	3.6
128	AIMMSCR	2017	Narula S, Tandon S, Singh SK, Tandon C. Kidney stone matrix proteins ameliorate calcium oxalate monohydrate induced apoptotic injury to renal epithelial cells. Life Sci. (2016) Sep 1. pii: S0024-3205(16)30497-0. doi: 10.1016/j.lfs.2016.08.026	Matrix proteins and COM injury	3.6
129	AIMMSCR	2017	Narula S, Tandon S, Baligar P, Singh SK, Tandon C. Human kidney stone matrix: Latent potential to restrain COM induced cytotoxicity and inflammatory response. Chem Biol Interact. 2017, 25;278:114-122. (IF- 3.14)	Immunology and Cell Biology	3.1
130	AIMMSCR	2017	Kaushik J, Tandon S, Gupta V, Nayyar J, Singla SK, Tandon C. Response surface methodology based extraction of Tribulus terrestris leads to an upsurge of antilithiatic potential by inhibition of calcium oxalate crystallization processes. PLoS One. (2017) Aug 28;12(8):e0183218Â	Preparation and validation of RSM extract against kidney stones	2.7
131	AIMMSCR	2017	Kumar D, et al., 2017. Development and characterization of an in vitro model for radiation-induced fibrosis,. Radiation Research. 189(3):326-336Â	radiation biology	2.5
132	AIMMSCR/AIB	2017	Khurana N, Kim H, Chandra PK, Talwar S, Sharma P, Abdel-Mageed AB, Sikka SC, Mondal D. Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer. Oncol Rep. 38(5): 2774-2786.	molecular therapeutics	2.662
133	AIMMSCR	2016	Ruchika Chauhan, Jay Singh, Tushar Sachdev, Tinku Basu, B.D. Malhotra “Recent advances in mycotoxin detection” J. Biosen Bioelectron (2016) 81, 532-545, DOI: 10.1016/j.bios.2016.03.004	Mycotoxin detection	10.2
134	AIMMSCR	2016	Abhishek Tyagi, Kanchan Vishnoi, Sutapa Mahata, Gaurav Verma, Shashank Masaldan, Alok C. Bharti, Bhudev C. Das. Cervical Cancer stem cell seltively overexpress HPV E6 oncoprotein that control stemness and self-renewal through upregulation of HES1, Clinical Cancer Research 22 (16), 4170-84. 2016)	cancer stem cell and regulation	10.1
135	AIMMSCR	2016	Sehrawat A, Roy R, Subrata K Pore et al, Mitochondrial dysfunction in cancer chemoprevention by phytochemicals from dietary and medicinal plants. 47:147-153	Phytochemicals, breast cancer, mitochondrial dysfunctionÂ	9.9
136	AIMMSCR	2016	Sheetal K. Bhardwaj, Premlata Yadav, Subhasis Ghosh, Tinku Basu, and Ajit Kumar Mahapatro “Biosensing test bed using Electrochemically deposited reduced Graphene oxide” Appl. Mater. Interf. (2016) 8 (37), 24350-24360, DOI: 10.1021/acsami.6b04562Â	biosensors	8.7
137	AIMMSCR	2016	Kumar Vinit, Palazzolo S, Bayda S, Corona G, Toffoli F, Rizzolio F, “DNA Nanotechnology for Cancer Theraputics” Theranostics, 6, 720-725, 2016.Â	DNA nanotechnology	8.5
138	AIMMSCR	2016	Kapoor S, Kundu SC. Silk protein-based hydrogels: Promising advanced materials for biomedical applications. Acta Biomater. 2016;31:17-32	Biomaterials and drug delivery	7.2
139	AIMMSCR	2016	Agarwal P, and Jackson SP. (2016) G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status. Cancer Letters 16;380(2):467-475	Cancer Epigenetics	6.5
140	AIMMSCR	2016	Ledgerwood LG*, Kumar D*, Eterovic AK, Wick J et al., 2016. The degree of intra-tumor mutational heterogeneity varies by primary tumor sub-site. Oncotarget. Mar 28. doi: 10.18632/oncotarget.8448.(	functional genomics and mutational analysis	6.4
141	AIMMSCR	2016	Kanojia D, Garg M and Koeffler HP. Potential targeted therapeutics approaches in liposarcoma. Editorial Review. Aging 2016; 8:569-70.Â	molecular therapeutics	6.4
142	AIMMSCR	2016	Rani R, Kumar Vinit, “Recent Update on Human Lactate Dehydrogenase Enzyme 5(hLDH5) Inhibitors: A Promising Approach for Cancer Chemitherapy” J. Med. Chem., 59, 487-496, 2016.	Drug discovery	6.2
143	AIMMSCR	2016	Shandilya J, Gao Y, Nayak TK, Roberts SGE, Medler KF AP1 transcription factors are required to maintain the peripheral taste system. Cell Death & Disease. 2016; 7:e2433.	Transcription regulation, Taste cell function	5.9
144	AIMMSCR	2016	Baligar P, Mukaherjee S, Veena K, Rastogi A, Mukhopadhyay A. Molecular and cellular functions distinguish superior therapeutic efficiency of bone marrow CD45 cells over mesenchymal stem cells in liver cirrhosis. Stem cells. 2016, 34:135–147. (IF-5.90)	stem cell biology	5.9
145	AIMMSCR	2016	Elvan Ergülen, Bálint Bécsi, István Csomós, László Fesüs and Kajal Kanchan* (2016) Identification of DNAJA1 as a novel interacting partner and a substrate of human transglutaminase 2. Biochemical Journal 473, 3889–3901. (*Corresponding author) [IF: 4.8]	protein biochemistry	4.8
146	AIMMSCR	2016	Kumar V, Ero R, Ahmed T, Goh KJ, Zhan Y, Bhushan S, and Gao YG (2016). Structure of the GTP form of elongation factor 4 (EF4) bound to the ribosome. Journal of Biological Chemistry (Cover Story). 291(25):12943-50	Ribosome	4.6
147	AIMMSCR	2016	Ero R, Kumar V, Chen Y, Gao YG (2016). Similarity and diversity of translational GTPase factors EF-G, EF4, and BipA: from structure to function. RNA Biology. 13(12):1258-1273 Â	Ribosome	4.6
148	AIMMSCR	2016	Kumar Vinit, Bayda S, Halda M, Caligiuri I, Spena CR, Palazzolo S, Kempter S, Corona G, Toffoli G, Rizzolio F, “Enhanced Chemotheraputic Behaviour of Open-Caged DNA@Doxorubicin Nanostructures for Cancer Cells” J. Cell. Phys. 231, 106-110, 2016.	Drug delivery	4
149	AIMMSCR	2016	The glucose metabolite methylglyoxal inhibits expression of the glucose transporter genes by inactivating the cell surface glucose sensors Rgt2 and Snf3 in yeast. Roy A, Hashmi S, Li Z, Dement AD, Cho KH, Kim JH. Mol Biol Cell. 2016 Mar 1;27(5):862-71. doi: 10.1091/mbc.E15-11-0789. Epub 2016 Jan 13. (IF: 3.905)	biosensors	3.9
150	AIMMSCR	2016	Alak nanda Mishra; Srikanth Iyer; Satya Pal Arya; Prakash Baligar; Silendra Arindkar; Ashwani kesarwani; Subeer Majumdar; Pramod Upadhayay; Jerald Mahesh Kumar, Nagarajan P. Role of antigen presenting cell invariant chain in the development of hepatic steatosis in mouse model. Experimental Cell Research. 2016, 346(2), 188-197. (IF-3.78).	mouse models	3.7
151	AIMMSCR	2016	Shandilya J, Medler KF, Roberts SG. Regulation of AURORA B function by mitotic checkpoint protein MAD2. Cell Cycle. 2016; 15:2196-2201.	Cell cycle checkpoint, protein kinase, Genomic stability	3.5
152	AIMMSCR	2016	Jalota A, Kumar M, Das BC, Yadav AK, Chosdol K, Sinha S. Synergistic increase in efficacy of a combination of 2-deoxy-D-glucose and cisplatin in normoxia and hypoxia: switch from autophagy to apoptosis, Tumour Biology, 37: 12347, 2016	Tumor Biology	3.3
153	AIMMSCR	2016	Shazia Rashid, L.Satyanarayana, Bhudev C. Das.  Knowledge, awareness and attitude on HPV, HPV vaccine and cervical cancer among college students in India.  Plos One, 18;11(11), 2016	Cervical Cancer	2.8
154	AIMMSCR	2016	Thakur S, Grover RK, Gupta S, Yadav AK, Das BC. Identification of Specific miRNA Signature in Paired Sera and Tissue Samples of Indian Women with Triple Negative Breast Cancer, Plos One, 11(7) e0158946, 2016	Breast Cancer	2.8
155	AIMMSCR	2016	Kashyap M#, Subrata K Pore#, Chancellor M, Yoshimura N, Tyagi P. Bladder overactivity involves overexpression of MicroRNA 132 and nerve growth factor. 167:98-104 (# equal)	microRNA in bladder overactivity, Liposome	2.7
156	AIMMSCR	2016	Kashyap M, Subrata K Pore, Yoshimura N, Tyagi P. Constitutive expression of NGF and P75NTR affected by bladder distension and NGF antisense treatment. 148:93-98	Nerve Growth Factor’s role in bladder, antisense treatment	2.7
157	AIMMSCR	2016	Mittal A, Tandon S, Singla SK, Tandon C. Mechanistic Insights into the Antilithiatic Proteins from Terminalia arjuna: A Proteomic Approach in Urolithiasis. PLoS One (2016) 20;11(9):e0162600. doi: 10.1371/journal.pone.0162600.Â	Proteomic based assessment of antilithiatic potentialÂ	2.7
158	AIMMSCR/AIB	2016	Khurana N, Talwar S, Chandra PK, Sharma P, Abdel-Mageed AB, Mondal D, Sikka SC. Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells. Int J Oncol. 49(4):1609-19.	molecular therapeutics	3.079
159	AIMMSCR/AIB	2016	Shazia Rashid, Satyanarayana Labani, Bhudev C Das; 2016 Knowledge, awareness and attitude on HPV, HPV vaccine and cervical cancer among the college students in India PLoS One. Nov 18;11(11):e0166713	HPV and cervical cancer	2.74
160	AIMMSCR/AIB	2016	Sudeep Bose et al., Regulation of Nucleolin Expression by HuR protein in Breast Cancer , cells MOL. Cell & Biochemistry, 417(1-2):141-53	breast cancer	2.8
161	AIMMSCR/AIB	2016	DK Singh, Sudeep Bose, Sachin Kumar, Regulation of Expression of miRNA by DNA Methylation in Lung cancer, Biomarkers 2016 21(7) 589-599	cancer biomarkers	2.5
162	AIMMSCR/AIB	2016	DK Singh, Sudeep Bose, Sachin Kumar, Role of microRNA in regulating cell cycle, cell signaling pathways and apoptosis in non-small lung cancer 2016 Current Molecular Medicine 16(5) 474-486	miRNA biology	2.4
163	AIMMSCR/AIB	2015	Simran J Kaur, Stephanie R McKeown, Shazia Rashid; Mutant SOD1 mediated pathogenesis of Amyotrophic Lateral Sclerosis; Gene. 2016 Feb 15;577(2):109-18	sclerosis pathogensis	2.98
164	AIMMSCR	2015	Gauri Shishodia, Gaurav Verma, Yogesh Srivastava, Bhudev Chandra Das,and Alok Chandra Bharti. Functional contribution of microRNAs Let-7a and miR-21 in aberrant STAT3 signaling in cervical cancer. Molecular Cancer. 12943-015-0385-22015	miRNA biology	15.3
165	AIMMSCR	2015	Gauri Shishodia,. Shirish Shukla, Yogesh Srivastava, Shashank Masaldan, Sumita Mehta, Suresh Bhambhani, Shashi Sharma, Ravi Mehrotra, Bhudev Chandra Das, Alok Chandra Bharti. Alterations in microRNAs miR-21 and let-7a correlate with aberrant STAT3 signaling and downstream effects during cervical carcinogenesis. Molecular Cancer14: 996	miRNA regulation	15.3
166	AIMMSCR	2015	Garg M*, Nagata Y, Kanojia D, Mayakonda A, Yoshida K, Jiang ZZ, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ding LW, Sampath A, Venkatesan S, Tan K, Sun QY, Lin DC, Chien W, Alpermann T, Inokuchi K, Wakita S, Yamaguchi H, Chng WJ, Yeoh A, Sanada M, Schiller J, Kreuzer KA, Kornblau SM, Kantarjian HM, Haferlach T, Lill M, Shih LY, Blau O, Yang H, Ogawa S, Koeffler HP. Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse. Blood 2015; 126:2491-501.Â	functional genomics	17.56
167	AIMMSCR	2015	Senapati P, Sudarshan D, Gadad SS, Shandilya J, Swaminathan V, Kundu TK. Methods to study histone chaperone function in nucleosome assembly and chromatin transcription. Methods in Molecular Biology (Clifton, N.J.); 1288:375-394, Humana press.	transcription regulation	10.7
168	AIMMSCR	2015	Akanksha Jalota, Mukesh Kumar, Bhudev C. Das, Ajay K. Yadav, Kunzang Chosdol and Subrata Sinha. Abrogating hypoxia chemoresistance in glioma cells by a combination of COX-2 inhibitor and Carmustine.Cancer LettersÂ	cancer resistance and recurrence	6.56
169	AIMMSCR	2015	Kanojia D, Nagata Y, Garg M, Lee DH, Sato A, Yoshida K, Sato Y, Sanada M, Mayakonda, Bartenhagen C, Klein HU, Doan NB, Said JW, Mohith S, Gunasekar S, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Myklebost O, Yang H, Dugas M, Meza-Zepeda LA, Silberman AW, Forscher C, Tyner JW, Ogawa S, Koeffler HP. Genomic landscape of liposarcoma. Oncotarget 2015; 6:42429-44.Â	genomics	6.4
170	AIMMSCR	2015	Garg M*, Okamoto R, Nagata Y, Kanojia D, Venkatesan S, Anand M.T, Braunstein GD, Said JW, Doan NB, Ho Q, Agaki T, Gery S, Liu LZ, Tan KT, Chng WJ, Yang H, Ogawa S, Koeffler HP. Establishment and characterization of novel human primary and metastatic anaplastic thyroid cancer cell lines and their genomic evolution over a year as a primagraft. Journal of Clinical Endocrinology and Metabolism 2015; 100:725-35.Â	genomics	6.2
171	AIMMSCR	2015	Transcription factor NF-κB associates with microtubules and stimulates apoptosis in response to suppression of microtubule dynamics in MCF-7 cells.  Rai A, Kapoor S, Singh S, Chatterji BP, Panda D.         Biochem Pharmacol. 2015;93:277-89Â	NF-κB signalling in Breast cancer	5.1
172	AIMMSCR	2015	Sahu N, Baligar P*, Midha S, Kundu B, Bhattacharjee M, Mukherjee S, Mukherjee S, Maushart F, Das S, Loparic M, Kundu SC, Ghosh S, Mukhopadhyay A. Nonmulberry Silk Fibroin Scaffold Shows Superior Osteoconductivity Than Mulberry Silk Fibroin in Calvarial Bone Regeneration. Adv Healthc Mater. 2015, 4(11), 1709-21.).	Tissue Engineering	5.1
173	AIMMSCR	2015	Veena Kochat, Sumod Kanjirakkuzhiyil1, Prakash Baligar, Perumal Nagarajan and Asok Mukhopadhyay. Donor antigen-primed regulatory T cells permit liver regeneration and phenotype correction in hemophilia A mouse by allogeneic bone marrow stem cells. Stem Cell Research & Therapy. 2015, 6,129	Stem Cells research and Therapy	4.2
174	AIMMSCR	2015	The Role of the Pleckstrin Homology Domain-containing Protein CKIP-1 in Activation of p21-activated Kinase 1 (PAK1). Kim YB, Shin YJ, Roy A, Kim JH, Journal of Biological Sciences	Protein kinase signalling, PAK-1, Casein kinase-1, Prostate cancer	4.1
175	AIMMSCR	2015	Shilpi Gupta, Prabhat Kumar, Harsimrut Kaur, Nishi Sharma, Daman Saluja, Alok C. Bharti and Bhudev C. Das. Selective participation of c-Jun with Fra-2/c-Fos promotes aggressive tumor phenotypes and poor prognosis in tongue cancer. Scientific Reports 5, 16811Â	cancer mechanisms	3.99
176	AIMMSCR	2015	Anoop Kumar, Showket Hussain, Gagan Sharma, Lutz Gissmann, Bhudev C Das and Mausumi Bharadwaj. Identification and validation of immunogenic potential of India specific HPV-16 variant constructs: In-silico & in-vivo insight to vaccine development.Scientific Reports5, 15751Â	virus mediated cancers	3.99
177	AIMMSCR	2015	Shandilya J, Roberts SGE. A role of WT1 in cell division and genomic stability. Cell Cycle;Â 14:1358-1364.	Cell cycle checkpoint, Tumor suppressor, Genomic stability	3.9
178	AIMMSCR	2015	Quantum Dots and their Potential Role in Cancer Theranostics. Tripathi SK, Kaur G, Khurana RK, Kapoor S, Singh B. Crit Rev Ther Drug Carrier Syst. 2015;32:461-502Â	Cancer Theranostics	3
179	AIMMSCR	2015	Ashwini N, Garg M, Mohan CD, Fuchs JE, Rangappa S, Anusha S, Swaroop TR, Rakes KS, Kanojia D, Madan V, Bender A, Koeffler HP, Basappa, Rangappa KS. Synthesis of 1,2-benzisoxazole tethered 1,2,3-triazoles that exhibit anticancer activity in acute myeloid leukemia cell lines by inhibiting histone deacetylases and including p21 and tubulin acetylation. Bioorganic and Medicinal Chemistry 2015; 23:6157-65.Â	molecular therapeutics	3
180	AIMMSCR	2015	Kirti Sharma, Atul Kathait, Asha Jain, Karmila Kujur, Shirish Raghuvanshi, Asha Chandola Saklani, Alok Chandra Bharti, Bhudev C Das. “Increased Prevalence of Human Papillomavirus Infection in Adolescent Girls Belonging to Different Indian Tribes with varied Socio-Sexual behavior”. Plos One, 1-13.Â	cancer epidemiology	2.74
181	AIMMSCR	2015	Assessing glucose uptake through the yeast hexose transporter 1 (Hxt1). Roy A, Dement AD, Cho KH, Kim JH. PLoS One	Nutrient sensing and signalling, glucose uptake and metabolism, glucose homeostasis	2.7
182	AIMMSCR	2015	Mishra A, Das BC. Curcumin as an anti-human papillomavirus and anti-cancer compound, FUTURE ONCOL., 11(18): 2487-90,Â	Phytochemicals	2.66