Events

Amity Institute of Biotechnology organized a guest lecture on a molecular mechanism for artemisinin-resistance in Plasmodium falciparum’ by Dr. Souvik Bhattacharjee of Special Centre for Molecular Medicine, JNU, New Delhi.

He talked about his work on the cellular targets of artemisinin in Plasmodium falciparum which has been a long standing question. His work showed that artemisinins were potent inhibitors of Plasmodium falciparum phosphatidylinositol-3-kinase (PfPI3K), revealing an unexpected mechanism of action. In resistant clinical strains, increased PfPI3K was associated with the C580Y mutation in P. falciparum Kelch13 (PfKelch13), a primary marker of artemisinin resistance. This work was published in the prestigious journal ‘Nature’ Dr. Bhattacharjee was invited and hosted by Dr. Krishna Murari Sinha Assistant professor  AIISHAmity University Gurgaon.

 30 Faculties and students of Biotechnology department attended the seminar. It was a very interactive session.